Protein Alignment Hmx and pnx

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_840087.1
• Gene: pnx / 352939
• ZFINID: ZDB-GENE-030328-42
• Length: 182
• Species: Danio rerio
• Alignment Length: 183
• Identity: 59/183 - (32%)
• Similarity: 83/183 - (45%)
• Gaps: 32/183 - (17%)

  Fly   401 TSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGE-----EIIEEDDGTDGPSDSSSPH 460
            ||:|:..|.:|.          |....|.|:..|.:.|..|     |..:....|..||..:..:
Zfish     5 TSNSTLQGKTSF----------SIADILDPAKFNGTRETREISNNRESPKTTSPTQEPSAPNIAN 59

  Fly   461 GDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR 525
            ......:.|:.||.|:..|:..||.:|....|||..||..:|::|.|:||||||||||||.|||:
Zfish    60 ASAAKVKSKRIRTAFTLDQLRILERSFQSSHYLSVFERHCIASALGLSETQVKIWFQNRRTKWKK 124

  Fly   526 QLAAELEAANMANMAHAA-QRLVRVPVLYHDGTTAGFVPPPPPHH--HPMQYY 575
                ||:.......:|.| ..|.:.|::|          ..|.||  |.:.||
Zfish   125 ----ELDGHGGEEQSHCAPTALTQNPIMY----------ALPGHHANHHVHYY 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	30/55 (55%)
pnx	NP_840087.1	Important for interaction with tle3a. /evidence=ECO:0000269|PubMed:12642490	1..34		10/38 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		8/38 (21%)
		Homeodomain	68..124	CDD:459649	30/55 (55%)