Protein Alignment Hmx and HOXD4

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 153
• Identity: 47/153 - (30%)
• Similarity: 66/153 - (43%)
• Gaps: 29/153 - (18%)

  Fly   400 PTSSSSSGGGSSLTHHPHPHLTGSHGGYL--------LPSSSNESDEEGEEIIEEDDGTDGPS-- 454
            |...|..|.||:|....|....|..||:.        .|.:...:...|.....:.|....||
Human    61 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGT 125

  Fly   455 -----------------DSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLA 502
                             :|.:|:..|.  ..|::||.::|.||.:||..|...|||:...|..:|
Human   126 ALKQPAVVYPWMKKVHVNSVNPNYTGG--EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIA 188

  Fly   503 ASLRLTETQVKIWFQNRRNKWKR 525
            .:|.|:|.|:||||||||.|||:
Human   189 HTLCLSERQIKIWFQNRRMKWKK 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	28/55 (51%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		15/65 (23%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeodomain	155..211	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		47/153 (31%)