Protein Alignment Hmx and HOXC4

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 60/212 - (28%)
• Similarity: 90/212 - (42%)
• Gaps: 54/212 - (25%)

  Fly   346 NQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQ-HPQQQQHPQQQQQQHPHQPTTPTSSSSSGGG 409
            :|.|..|.|.|.:     .|..::...|..||: :|.....|...::|:       :.:|..|.|
Human    24 SQNSYIPEHSPEY-----YGRTRESGFQHHHQELYPPPPPRPSYPERQY-------SCTSLQGPG 76

  Fly   410 SSLTH------HPHPHLTGS-------HGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSS--- 458
            :|..|      |.||..:.|       .|....||.:..:..:        ...|.||.::|
Human    77 NSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQ--------PAPDHPSSAASKQP 133

  Fly   459 ---------------PHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLT 508
                           |:.:|.  ..|::||.::|.||.:||..|...|||:...|..:|.||.|:
Human   134 IVYPWMKKIHVSTVNPNYNGG--EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLS 196

  Fly   509 ETQVKIWFQNRRNKWKR 525
            |.|:||||||||.|||:
Human   197 ERQIKIWFQNRRMKWKK 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	29/55 (53%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		27/125 (22%)
		Antp-type hexapeptide	135..140		0/4 (0%)
		Homeodomain	157..213	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		60/212 (28%)