Protein Alignment Hmx and HOXB9

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 75/313 - (23%)
• Similarity: 113/313 - (36%)
• Gaps: 89/313 - (28%)

  Fly   228 SNGFTSFSISSILS-RSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRY 291
            |...:|:.:.||:| .||.|                 |.|..|                  :|:|
Human     4 SGTLSSYYVDSIISHESEDA-----------------PPAKFP------------------SGQY 33

  Fly   292 AALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSP---TSMSPNNNNNNSNTTASSNQASKSPS 353
            |:...||   ..:.|.|.|         .:..|.:|   .|.:|          .|.:.:...||
Human    34 ASSRQPG---HAEHLEFPS---------CSFQPKAPVFGASWAP----------LSPHASGSLPS 76

  Fly   354 HHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHP 418
            .:  ||...|.|..            |.:.::.:...:..|.....|....::.....|...|..
Human    77 VY--HPYIQPQGVP------------PAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGE 127

  Fly   419 HLTGSHGGYLLPSS-------SNESDEEGE-EIIEEDDGTDGPSDSSSPHGD---GNSKRKKKTR 472
            .|......|.|.:|       ||:....|: :|.|..:..:.| |.::|..:   ..|.|||  |
Human   128 LLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERP-DQTNPSANWLHARSSRKK--R 189

  Fly   473 TVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR 525
            ..:::.|..:||..|....||:...|..:|..|.|:|.||||||||||.|.|:
Human   190 CPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	24/55 (44%)
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	45/239 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		11/63 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		8/33 (24%)
		Homeodomain	186..242	CDD:459649	26/57 (46%)