Protein Alignment Hmx and pdx1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_571518.2
• Gene: pdx1 / 30721
• ZFINID: ZDB-GENE-990415-122
• Length: 246
• Species: Danio rerio
• Alignment Length: 349
• Identity: 84/349 - (24%)
• Similarity: 116/349 - (33%)
• Gaps: 150/349 - (42%)

  Fly   308 FHSPTH---DS------SSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLY-H 362
            ::.|.|   ||      .:.:.::|||....|               .||         |.:| .
Zfish     7 YYPPNHLYKDSCAFQRHPNEDYSQNPPPCLYM---------------RQA---------HSVYAS 47

  Fly   363 PLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQP-TTPTSSSSSGG-GSSLT--------HHPH 417
            |||:|.|.........:...:   ......|.|.| |:.||..|.|| |.||.        |.|.
Zfish    48 PLGAQDQPNLTDITSYNMSSR---DDLAGPHLHLPQTSQTSLQSLGGYGDSLDLCGDRNRYHLPF 109

  Fly   418 PHL--TGSH---------GGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKT 471
            |.:  |.||         |.|::.:..|                                  |:|
Zfish   110 PWMKSTKSHTHAWKGQWTGPYMVEAEEN----------------------------------KRT 140

  Fly   472 RTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANM 536
            ||.::|||:.:||..|...:|:|...|..||.:|.|||..:||||||||.|||::
Zfish   141 RTAYTRAQLLELEKEFLFNKYISRPRRVELALTLSLTERHIKIWFQNRRMKWKKE---------- 195

  Fly   537 ANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAAARNTSPPRPPLSSLVXG----VGC 597
                                                :....||...|.:.  ||:..|    ..|
Zfish   196 ------------------------------------EDKRRARGVDPEQD--SSITSGDLKDESC 222

  Fly   598 LATAPMSLLKPPNSMAHPPHPQPP 621
            :.||  :|..||:    |.||..|
Zfish   223 VGTA--TLAGPPS----PLHPHAP 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	29/55 (53%)
pdx1	NP_571518.2	Homeodomain	138..194	CDD:459649	29/55 (53%)