Protein Alignment Hmx and nkx2.7

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_571494.1
• Gene: nkx2.7 / 30694
• ZFINID: ZDB-GENE-990415-179
• Length: 269
• Species: Danio rerio
• Alignment Length: 227
• Identity: 74/227 - (32%)
• Similarity: 99/227 - (43%)
• Gaps: 30/227 - (13%)

  Fly   373 QQQHQQHP------QQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSH---GGYL 428
            :||...:|      :|...|.|..|....|.|...|       ..|.:.|...:.|..   ..:.
Zfish    20 EQQQALNPGVFMGVEQDSVPLQSLQLQCMQNTLSRS-------LDLLYSPEKGIPGEQVKCDDFD 77

  Fly   429 LPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKK-------KTRTVFSRAQVFQLEST 486
            :..||..|..|.|....|:......:|||....:|.:.|:|       |.|.:||:.|||:||..
Zfish    78 IVRSSCGSPTEEEMDANEETSMCPFTDSSYSSKNGETLREKPKQRLRRKPRVLFSQTQVFELERR 142

  Fly   487 FDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPV 551
            |..:||||:.||..||.:|:||.|||||||||||.|.|||...:       ::..|..|.|.|||
Zfish   143 FKQQRYLSAPERDHLALALKLTSTQVKIWFQNRRYKCKRQRQDK-------SLELAGPRRVAVPV 200

  Fly   552 LYHDGTTAGFVPPPPPHHHPMQYYAAARNTSP 583
            |..||......|......:|...|..:...:|
Zfish   201 LVRDGKPCHGAPYNVTVSYPYNNYYNSYGNNP 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	34/62 (55%)
nkx2.7	NP_571494.1	COG5576	87..210	CDD:227863	54/129 (42%)
		Homeodomain	125..181	CDD:459649	33/55 (60%)