Protein Alignment Hmx and Dlx1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001094001.1
• Gene: Dlx1 / 296500
• RGDID: 1309593
• Length: 255
• Species: Rattus norvegicus
• Alignment Length: 230
• Identity: 74/230 - (32%)
• Similarity: 104/230 - (45%)
• Gaps: 41/230 - (17%)

  Fly   380 PQQQQHPQQQQQQH----------PHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGG--YLLPSS 432
            |.||..|......|          ..||....||:||  .|....:|:.:...||..  |:   |
  Rat    26 PNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASS--FSRPLGYPYVNSVSSHASSPYI---S 85

  Fly   433 SNESDEEGEEIIE---EDDGTDGPSDSSSPHGD----GNSKRKKKTRTVFSRAQVFQLESTFDLK 490
            |.:|......:.:   ||.|.|....:....|:    |..|:.:|.||::|..|:..|...|...
  Rat    86 SVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQT 150

  Fly   491 RYLSSSERAGLAASLRLTETQVKIWFQNRRNKWK---RQLAAELEAANMANMAHAAQRLVRVPVL 552
            :||:..|||.|||||.||:|||||||||:|:|:|   :|..|.||.:.:||....:.....||..
  Rat   151 QYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPG 215

  Fly   553 YH--------DGTTAG-FVPP-----PPPHHHPMQ 573
            ::        .|::|| :||.     |..|...||
  Rat   216 WNPNSSSGKGSGSSAGSYVPSYTSWYPSAHQEAMQ 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	31/58 (53%)
Dlx1	NP_001094001.1	Homeodomain	129..185	CDD:459649	30/55 (55%)