Protein Alignment Hmx and Hmx3

DIOPT Version :9

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001099772.1
• Gene: Hmx3 / 293537
• RGDID: 1559927
• Length: 356
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 150/499 - (30%)
• Similarity: 195/499 - (39%)
• Gaps: 203/499 - (40%)

  Fly   156 SPPMKSPERNGGDEVQGHSLNNNNSKALNHNN---------------TCASAAAAAAAAAVAAAN 205
            :||.:.|.:....:....|:.|    .||.::               ..|||||||||||.|||
  Rat    14 APPPQPPPQPPAPKESPFSIRN----LLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAA- 73

  Fly   206 LSNNSNDSNGSSGGGGG--KSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQLPQPGAGG 268
                    .|:..|..|  .|..|...|..|.|        ||::..          ||
  Rat    74 --------KGALEGAAGFALSQVGDLAFPRFEI--------PAQRFA----------LP------ 106

  Fly   269 PQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRLP---FHSPTHDSS----------STNT 320
               |..|.|                  .|.| |.|..|.   .|.|..::|          ::.|
  Rat   107 ---AHYLER------------------SPAW-WYPYTLTPAGGHLPRPEASEKALLRDSSPASGT 149

  Fly   321 TENPPSP-TSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQ 384
            ..:.|.| ....|::...:          ||||....|           ::...::.::..:
  Rat   150 DRDSPDPLLKADPDHKELD----------SKSPDEIIL-----------EESDSEEGKKEGE--- 190

  Fly   385 HPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEED-- 447
                         ..|.::.::.|.::.|                |.|             ||
  Rat   191 -------------AVPGAAGTTVGATAAT----------------PGS-------------EDWK 213

  Fly   448 DGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQV 512
            .|.|.|....       :.|||||||||||:||||||||||:||||||||||||||||.||||||
  Rat   214 AGADSPEKKP-------ACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQV 271

  Fly   513 KIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAA 577
            |||||||||||||||||||||||:::.  ||||:||||:|||:.:.|
  Rat   272 KIWFQNRRNKWKRQLAAELEAANLSHA--AAQRIVRVPILYHENSAA------------------ 316

  Fly   578 ARNTSPPRPPLSSLVXGVGCLATAPMSLLKPPNSMAHP---PHP 618
                            |....|.||:.:.:|..:..||   .||
  Rat   317 ---------------EGAAAAAGAPVPVSQPLLTFPHPVYYSHP 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeobox	471..524	CDD:278475	49/52 (94%)
Hmx3	NP_001099772.1	Homeobox	230..284	CDD:395001	50/53 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6101
eggNOG	1	0.900	-	-		E1_KOG0485
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003349
OrthoInspector	1	1.000	-	-		otm44413
orthoMCL	1	0.900	-	-		OOG6_109246
Panther	1	1.100	-	-	O	PTHR46110
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X983
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.900