Protein Alignment Hmx and Dbx1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001009644.1
• Gene: Dbx1 / 292934
• RGDID: 1308896
• Length: 335
• Species: Rattus norvegicus
• Alignment Length: 457
• Identity: 103/457 - (22%)
• Similarity: 147/457 - (32%)
• Gaps: 167/457 - (36%)

  Fly   253 GLITP---IPQL--PQPGAGGPQDAAMLSRLGFISQWGALAGRYAALC--------PPGWPWAPQ 304
            ||:.|   .|.|  |.|....||           |...|.:|..:.|.        ||.:
  Rat     5 GLLAPPAGYPSLLRPTPTLTLPQ-----------SLQSAFSGHSSFLVEDLIRISRPPTY----- 53

  Fly   305 RLPFHSPTHDSSSTNTTENPP---SPTSMSPNNNNN-----NSNTTASSNQASKSPSHHPLHPLY 361
             ||...||...|       ||   :||:::.:..::     :.:...||.|.:.||:.   .|.:
  Rat    54 -LPRSIPTASLS-------PPRQEAPTALADSGTSDLGSPGSGSRRGSSPQTALSPAS---EPTF 107

  Fly   362 HPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGG 426
            ...|.........:.:..|...|.|         .|.|               ...|:..||...
  Rat   108 LKFGVNAILSSAPRRETSPALLQSP---------PPKT---------------FAFPYFEGSFQP 148

  Fly   427 YL----LPSSSNESDEEGEEIIEEDDGTDGPSDSSSP-HGDGNSKRKKKTRTVFSRAQVFQLEST 486
            ::    .|:||:.              ...|...|.| ...|..:|....|.|||..|...||.|
  Rat   149 FIRSSYFPASSSV--------------VPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKT 199

  Fly   487 FDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPV 551
            |..::|:|..:|..||:.|.|.::||||||||||.||:.....||.::.
  Rat   200 FQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSG---------------- 248

  Fly   552 LYHDGTTAGFVPPPPPHHHPMQYYAAARNTSP----PRPPLSSLVXGVGCLATAPMSLLKPPNSM 612
                                    .....|.|    |.|.||.    ||...........|..|:
  Rat   249 ------------------------GCREQTLPTKLNPHPDLSD----VGQKGPGDEEEDSPGASL 285

  Fly   613 AH--PPHPQ-----PPPPAPLHMQQRSFLGCEQLTETDMDSDSEQERSHMMDDEDAAIDVEADEE 670
            |:  ||.|:     |.|.:|.|                  |.|..:.|...|.::   |.|.:|:
  Rat   286 AYHAPPDPRHLLEGPLPASPAH------------------SSSPGKPSDFSDSDE---DEEGEED 329

  Fly   671 QE 672
            :|
  Rat   330 EE 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	28/55 (51%)
Dbx1	NP_001009644.1	PRK12323	<49..182	CDD:481241	34/186 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..102		11/52 (21%)
		Homeodomain	184..238	CDD:459649	28/53 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..335		28/157 (18%)