Protein Alignment Hmx and Gbx1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001258382.1
• Gene: Gbx1 / 246149
• RGDID: 621864
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 110/463 - (23%)
• Similarity: 166/463 - (35%)
• Gaps: 133/463 - (28%)

  Fly   156 SPPMK--SPERNGGDEVQGHSLNNNNSKALN---HNNTCASAAAAAAAAAVAAANLSNNSNDSNG 215
            |||.:  .|...|....:.|.......:.|.   .:..|.||..|......|....:     ..|
  Rat     9 SPPARPLPPYERGSAAPEPHCAEPAPRRYLGPRARSEPCVSAPGARRGPGSAMQRAA-----GGG 68

  Fly   216 SSGGGGGKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQ--------LPQPGAGGPQDA 272
            :.||.||   :|....|:|||.|::  ..|..::|.. |.|..|.        |||..|..|..|
  Rat    69 APGGSGG---SGGGPGTAFSIDSLI--GPPPPRSGHL-LYTGYPMFMPYRPLVLPQALAPAPLPA 127

  Fly   273 AMLSRLGFISQWGALAGRYAA-------------------LCPPGWPWAPQRLPFHSPTHDSSST 318
            .:.......|..|.|:..:.|                   ..||...:.|..|...:....:|:.
  Rat   128 GLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAAAAAASTV 192

  Fly   319 N--------------------------TTENPPSPTSMSPNNNNNNSNTTA-----SSNQASKSP 352
            :                          .||.||.|....|:.:....:..|     ||::....|
  Rat   193 SRSNPEPPARRTDGALDADELLPAREKVTEPPPPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEP 257

  Fly   353 SHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPH 417
                  |...|.||:.:::......:                     .:...||.||......|.
  Rat   258 ------PAGEPAGSEPEEEGSGGDSE---------------------DSFLDSSAGGPGALLGPK 295

  Fly   418 PHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQ 482
            |.|.||.|             .|.|     :||...:..::|.|     :.::.||.|:..|:.:
  Rat   296 PKLKGSLG-------------TGAE-----EGTPVATGVTTPGG-----KSRRRRTAFTSEQLLE 337

  Fly   483 LESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQR-- 545
            ||..|..|:|||.:||:.:|.:|:|:|.||||||||||.||||     ::|.|:::.:....|
  Rat   338 LEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR-----IKAGNVSSRSGEPVRNP 397

  Fly   546 --LVRVPV 551
              :|.:||
  Rat   398 KIVVPIPV 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	29/55 (53%)
Gbx1	NP_001258382.1	Homeodomain	324..380	CDD:459649	29/55 (53%)