Protein Alignment Hmx and Hoxc10

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_034592.2
• Gene: Hoxc10 / 209448
• MGIID: 96192
• Length: 342
• Species: Mus musculus
• Alignment Length: 317
• Identity: 72/317 - (22%)
• Similarity: 113/317 - (35%)
• Gaps: 92/317 - (29%)

  Fly   259 PQLPQPGAGGPQDAAMLSRLGFISQ---WGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNT 320
            |.|.:...||..:.|:.:...::||   ||.....|....|.|
Mouse    51 PSLSKRDEGGSPNLALNTYPSYLSQLDSWGDPKAAYRLEQPVG---------------------- 93

  Fly   321 TENPPSPTSMSPNNNNNNSNTTASSNQASKS-----------------------PSHHPLHPLY- 361
              .|.|..|..|:....|.....|:.:.:||                       ||::...|.|
Mouse    94 --RPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYS 156

  Fly   362 ------HPLGSQQQQQQQQQ---------HQQHPQ---QQQHPQ--QQQQQHPHQPTTPTSSSSS 406
                  |..|:.:.:...:|         |.:.||   :...|:  :...|.|......|..|.:
Mouse   157 ALDKTPHCAGANEFEAPFEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLA 221

  Fly   407 GGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGN---SKRK 468
            |..:|      |..:.........||.:.||.|.:|.|:.::.|            ||   :|..
Mouse   222 GPKAS------PSESEKERAKTADSSPDTSDNEAKEEIKAENTT------------GNWLTAKSG 268

  Fly   469 KKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR 525
            :|.|..:::.|..:||..|....||:...|..::.::.||:.||||||||||.|.|:
Mouse   269 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	22/55 (40%)
Hoxc10	NP_034592.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..271		22/102 (22%)
		Homeodomain	269..325	CDD:459649	22/55 (40%)