Protein Alignment Hmx and nob-1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001369824.1
• Gene: nob-1 / 176641
• WormBaseID: WBGene00003779
• Length: 243
• Species: Caenorhabditis elegans
• Alignment Length: 278
• Identity: 65/278 - (23%)
• Similarity: 102/278 - (36%)
• Gaps: 95/278 - (34%)

  Fly   299 WPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHP------- 356
            ||.|...:|  |...:|.|...:|...|| .::|::.......||  ......||..|
 Worm    31 WPSAAAAIP--SIQGESRSERESETGSSP-QLAPSSTGMVMPGTA--GMYGFGPSRMPTANEFGM 90

  Fly   357 -LHPLY-----HPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHH 415
             ::|:|     :||.|.......|                   |:|.|              .::
 Worm    91 MMNPVYTDFYQNPLASTGWYSYGQ-------------------PYQFT--------------ANY 122

  Fly   416 PHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHG----------DGNSKRKKK 470
            ..|.|.|:.....:|:                  |.|.|.:::|:.          ||     ||
 Worm   123 SIPSLDGNLSDITIPT------------------TAGSSAATTPNAAMHLPWAISHDG-----KK 164

  Fly   471 TRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAAN 535
            .|..:.:.|:.:||..:.:.:||::..|:.|:|.|.|.|.|||:||||||.|.|:     |...:
 Worm   165 KRQPYKKDQISRLEYEYSVNQYLTNKRRSELSAQLMLDEKQVKVWFQNRRMKDKK-----LRQRH 224

  Fly   536 MANMAHAA------QRLV 547
            .....|.|      :||:
 Worm   225 SGPFPHGAPVTPCIERLI 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	24/55 (44%)
nob-1	NP_001369824.1	Homeodomain	163..219	CDD:459649	24/55 (44%)