Protein Alignment Hmx and Hmx2

DIOPT Version :9

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001355289.1
• Gene: Hmx2 / 15372
• MGIID: 107159
• Length: 273
• Species: Mus musculus
• Alignment Length: 373
• Identity: 128/373 - (34%)
• Similarity: 158/373 - (42%)
• Gaps: 132/373 - (35%)

  Fly   222 GKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGA 286
            ||....:.|.:||:|.|||                         .|||.:|...
Mouse     8 GKGCPAAGGVSSFTIQSIL-------------------------GGGPSEAPRE----------- 36

  Fly   287 LAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPP-----SPTSMSPNNNNNNSNTTASSN 346
                     |.||| |.:|         |.|.::.|..|     :|....|:.:          .
Mouse    37 ---------PAGWP-ARKR---------SLSVSSEEEEPEEGWKAPACFCPDPH----------G 72

  Fly   347 QASKSPSHHPLHPLYHP-LGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGS 410
            ....||.||.  |:..| ||                                 ||   ..|||..
Mouse    73 PKEPSPKHHT--PIPFPCLG---------------------------------TP---KGSGGAG 99

  Fly   411 SLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKR-----KKK 470
            .......|.|:.||..:         .||.|.::.....:.||   ..|. ||.::|     |||
Mouse   100 PAASERTPFLSPSHPDF---------KEEKERLLPAGSPSPGP---ERPR-DGGAERQTGAAKKK 151

  Fly   471 TRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAAN 535
            |||||||:||:|||||||:||||||||||.||:||:|||||||.|||||||||||||:|||||
Mouse   152 TRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEA-- 214

  Fly   536 MANMAHA-AQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAAARNTS 582
             |||||| ||.||.:|:::.|.:... ||.|.....|...|..:.|.|
Mouse   215 -ANMAHASAQTLVGMPLVFRDSSLLR-VPVPRSLAFPAPLYYPSSNLS 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeobox	471..524	CDD:278475	45/52 (87%)
Hmx2	NP_001355289.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..154		55/261 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0485
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46110
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4603
SonicParanoid	1	1.000	-	-		X983
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.900