Protein Alignment Hmx and Dlx4

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_031893.3
• Gene: Dlx4 / 13394
• MGIID: 94904
• Length: 240
• Species: Mus musculus
• Alignment Length: 231
• Identity: 67/231 - (29%)
• Similarity: 91/231 - (39%)
• Gaps: 68/231 - (29%)

  Fly   306 LPFHSPTHDSSSTNTTENPPS-------PTSMSPNNNNNNSNTTASSNQASKSPSH-HPLHPLYH 362
            ||...|...:|:....:..|:       |..:||.        ||:|...|.|.|: || ....|
Mouse     4 LPCPLPDRGASNVVFPDLAPALSVVAAYPLGLSPG--------TAASPDLSYSQSYGHP-RSYSH 59

  Fly   363 PLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGY 427
            |            ....|.....|:|||...|.||               .|.|..|
Mouse    60 P------------GPATPGDSYLPRQQQLVAPSQP---------------FHRPAEH-------- 89

  Fly   428 LLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRK-KKTRTVFSRAQVFQLESTFDLKR 491
                 ..|.:.|.|::          :.|..|....:..|| :|.||::|..|:..|...|...:
Mouse    90 -----PQELEAESEKL----------ALSLVPSQQQSLTRKLRKPRTIYSSLQLQHLNQRFQHTQ 139

  Fly   492 YLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQL 527
            ||:..|||.|||.|.||:|||||||||:|:|:|:.|
Mouse   140 YLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLL 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	29/55 (53%)
Dlx4	NP_031893.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..70		8/38 (21%)
		Homeodomain	117..173	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..194		1/1 (100%)