Protein Alignment Hmx and LOC1280263

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_061512032.1
• Gene: LOC1280263 / 1280263
• VectorBaseID: AGAMI1_003435
• Length: 637
• Species: Anopheles gambiae
• Alignment Length: 671
• Identity: 149/671 - (22%)
• Similarity: 227/671 - (33%)
• Gaps: 263/671 - (39%)

  Fly   189 CASAAAAAAAA----AVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSRSEPAKKN 249
            |.|.:|.|.|.    ::......|:        |.|||             ::|:...:.|:::.
Mosquito    37 CKSPSATAIAVKTPFSIEDILFQND--------GAGGG-------------VASVGHPNSPSRER 80

  Fly   250 GAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQW-----------GALAGRYAALCPPGWPWAP 303
            .|.|.:..:|.  .||||   |...|...|..|:.           ||.:|
Mosquito    81 LAGGSVRTVPS--SPGAG---DQRSLESDGDESELDDTLAEVVLPSGATSG-------------- 126

  Fly   304 QRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQAS------------KSPSHHP 356
                     |:.|.:::..   |....|.....|.|.:..:|.:||            ..|..:.
Mosquito   127 ---------HERSKSSSEF---SEVGDSAQRGGNQSQSGGNSIKASGDVVGGAVRGKTGGPDGNG 179

  Fly   357 LHPLYHPLGSQQQQQQQQQHQQHPQQ-----QQHPQQQQQQHP---------HQPTTPTSS---- 403
            |      :.:.::||.::....|.::     ...|...||..|         |.|..|.::
Mosquito   180 L------VRNGEEQQYRKATVLHSERFASKLNLDPSTPQQSSPVTVPPPRIQHPPPPPPAAPPAP 238

  Fly   404 --SSSGG----------GSSLTHHPHP---HLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGP 453
              |||||          |...|.:|:.   :|..:.|.||.||::      |.:.::....:.|
Mosquito   239 PVSSSGGPVQFTSGPSAGVMYTTNPYSDPGYLQMALGAYLAPSAT------GYKTVDPYFLSQG- 296

  Fly   454 SDSSSP-------------HGDGNSK----RKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGL 501
            ..:|||             .|.|.|.    |::|.|||||..|:..||..|:.:||||:.||..|
Mosquito   297 IFASSPLFPGAGCPDIALGLGMGMSALRHCRRRKARTVFSDPQLTGLEKRFEAQRYLSTPERVEL 361

  Fly   502 AASLRLTETQVKIWFQNRRNKWKRQL-AAELEAA------------------------NMANMAH 541
            |::|.|:|||||.||||||.|.|:|| ..|:.||                        :.::::.
Mosquito   362 ASALGLSETQVKTWFQNRRMKHKKQLRRREVNAADNNGSSGTGATAGGSSTNSSTSSSSSSSLSS 426

  Fly   542 AAQRLVRVPVLYHDG--------TTAGFVPPPPPHHHPMQYYAAARNTS---------PPR---- 585
            .:.||...|.....|        :::|...|||........|:..:.|:         ||.
Mosquito   427 TSSRLHGPPAAPSSGSAGSTGSSSSSGSSGPPPAERSSFTSYSNGKGTTGLSHGGAKPPPSSTSS 491

  Fly   586 -----------PPLSSLVXG-----------------VGCLATAPMSLLKP-----------PNS 611
                       .||||...|                 ....|.|..:.|.|           .|.
Mosquito   492 SGSSSSASGVLKPLSSASSGSMHSSFSLVKRSAAAAAAAAAAAAAAAALGPGGNGSLHHPFHSNH 556

  Fly   612 MAHPPHPQPPPPAPLHMQQR------SFLGCEQLTE------------------TDMDSDSEQER 652
            .:||.||...|    |.||:      ..|....|.:                  |...||.|
Mosquito   557 HSHPHHPHHLP----HQQQQHQGGHHHLLAAHHLAQLGGQPPSGGNHNHHHHHRTPPSSDDE--- 614

  Fly   653 SHMMDDED---AAIDVEADEE 670
              :|:|.|   :.:|:..|::
Mosquito   615 --LMNDSDSDCSDVDIVGDDQ 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	32/55 (58%)
LOC1280263	XP_061512032.1	None