Protein Alignment Hmx and LOC1277926

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_317438.4
• Gene: LOC1277926 / 1277926
• VectorBaseID: AGAMI1_003079
• Length: 596
• Species: Anopheles gambiae
• Alignment Length: 664
• Identity: 150/664 - (22%)
• Similarity: 210/664 - (31%)
• Gaps: 228/664 - (34%)

  Fly    26 RDSPLLARSPARSADGSSPPATPT-----HRSNTPNTAAGTPTTSASGGN--------------- 70
            |.||..|.||......|..|.:.|     ..|..|.....|.|||.||.:
Mosquito     6 RCSPQSAPSPPHHHHSSQSPTSTTTVTMATASPVPACTTTTSTTSTSGASAASSPTRDEMSLVVP 70

  Fly    71 ----HFHHSPSG--GAVPPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGATHPALLQHA 129
                |....|.|  |.:|....|||...|...|..||   ||..|.  ...|:...:.||.:..:
Mosquito    71 ISPLHIKQEPLGSDGPMPAQPPHHHQHPHHHQLPHHP---HHQHHP--QQQPSPQTSPPASISFS 130

  Fly   130 LT---------PTGQQQQQQLQVQQQHQQSHV--ERLSPP-------MKSPERNGGDEVQGHSLN 176
            :|         .|.:||      ||.|.||..  |.:||.       :..|:         |.|:
Mosquito   131 ITNILSDRFGKATAEQQ------QQPHPQSPAIREPISPGPIHPAVLLPYPQ---------HVLH 180

  Fly   177 NNNSKALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILS 241
            ..:..||.|
Mosquito   181 PAHHPALLH-------------------------------------------------------- 189

  Fly   242 RSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRL 306
               ||...|......|.|..|||....||.|::..|......:.  ..:...||......:...|
Mosquito   190 ---PAYHTGLHHYYQPSPSHPQPIVPQPQRASLERRDSLFRPYD--ISKSPRLCSSNGSSSATPL 249

  Fly   307 PFHSPTHDSS--STNTTENPPSPTS----MSPNNNNNNSNT--TASSNQASKSPSHHPLHPLYHP 363
            |.| |.|..|  ||..:.:.|||.:    .||::.::...|  |.||...|..........|.|.
Mosquito   250 PLH-PYHTDSDCSTQDSTSAPSPATYGDIASPSSASSAMTTPATTSSPTGSVYDYSRKASALDHR 313

  Fly   364 L----GSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHP------ 418
            .    |........:.|::.....:..|.:..:...:.....:::::...:|.|.|..|
Mosquito   314 AALLNGFSAAASYPKLHEEIINSHRKFQAKLIESQTKAALAAAATAAAAAASATPHNMPPLGSLC 378

  Fly   419 --------HLTG--------------SHGGYLLP---------------------SSSNE----- 435
                    |:.|              |:||...|                     |||.:
Mosquito   379 KTVSQIGQHVAGTGSLNGSGSATNGASNGGSGAPATAKPTPKPIPKPAPSSETNGSSSQDAGMES 443

  Fly   436 SDEEGEEIIEEDDGTDGPSD---------------SSSPH----------GDGNSKRKKKTRTVF 475
            ||:...|.....||::..|:               ||.|.          ||...||   .||.|
Mosquito   444 SDDAKSETSSTKDGSENGSNLWPAWVYCTRYSDRPSSGPRYRRTKQPKEKGDSEEKR---PRTAF 505

  Fly   476 SRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQ------LAAELEAA 534
            |.||:.:|::.|:..|||:...|..|:|.|.|.|.|:||||||:|.|.|:.      ||.:|.|.
Mosquito   506 SNAQLQRLKNEFNENRYLTEKRRQTLSAELGLNEAQIKIWFQNKRAKIKKSSSEKNPLALQLMAQ 570

  Fly   535 NMANMAHAAQRLVR 548
            .:.|  |:...|.:
Mosquito   571 GLYN--HSTVPLTK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	26/55 (47%)
LOC1277926	XP_317438.4	None