Protein Alignment Hmx and Hmx

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_310605.6
• Gene: Hmx / 1271752
• VectorBaseID: AGAMI1_000155
• Length: 598
• Species: Anopheles gambiae
• Alignment Length: 727
• Identity: 298/727 - (40%)
• Similarity: 340/727 - (46%)
• Gaps: 270/727 - (37%)

  Fly     1 MSSSEAEVDISVVSSPEPSPLGAAARDSPLLARSPARSADGSSPPATPTHRSNTPNTAAGTPTTS 65
            |||.|.::|::|||||||||   ...|||              ||..|           |:....
Mosquito     7 MSSPEVDIDVNVVSSPEPSP---RPLDSP--------------PPGQP-----------GSDDEQ 43

  Fly    66 ASGGNHFHHSPSGGAV-----PPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGATHPAL 125
            .|..:..||:.||.:.     ||..|...|...|.                        |||
Mosquito    44 RSSPDTQHHNQSGYSAPSQQQPPPSLPPPLPQQLK------------------------ATH--- 81

  Fly   126 LQHALTPTGQQQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNSKALNHNNTCA 190
                 :||.|||||......||.|||   |||       :||    ||      ...|.|::...
Mosquito    82 -----SPTLQQQQQPHHNHHQHHQSH---LSP-------HGG----GH------GAVLQHHSAMV 121

  Fly   191 SAAAAAAA----AAVAAA---------------------------NLSNNS---NDSNGSSGGG- 220
            :|||||||    ||.|||                           ..|:||   |.:|.||...
Mosquito   122 AAAAAAAALHHQAAQAAAAQAAGQHGCGSYHVVGSPAAAIPPAIPAASSNSSAINSTNSSSTNSF 186

  Fly   221 ----------------------------------------------------------------- 220
                                                                             
Mosquito   187 NHSPDSRLSPPKTPPESQHQHQHHHAQQQHHQHPAHQHPPHHTHTHINQLSHQTQQQQQQQQQSP 251

  Fly   221 -GGKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQLPQPGA------------------ 266
             .||:.| :.|:|||||||||||:||..|.| .|:|||:|.||...|
Mosquito   252 TVGKTAT-NPGYTSFSISSILSRTEPVAKKG-LGVITPVPSLPLSAAAAAAAAAASVSNGTVSLG 314

  Fly   267 --GGP--QDAAMLSRLGFISQWGALAGRYAALCPPGWPWAP--QRLPFHSPTHDSSSTNTTENPP 325
              |.|  |||||||||||:|||.|:|.||||||||||||.|  .|:||||||:| :|||..||
Mosquito   315 SNGTPSTQDAAMLSRLGFMSQWSAIANRYAALCPPGWPWPPTSHRMPFHSPTND-NSTNAMEN-- 376

  Fly   326 SPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQ 390
                .||       :.|...:|.|||||.||..     ||.:
Mosquito   377 ----QSP-------SLTPPPSQQSKSPSPHPAF-----LGGR----------------------- 402

  Fly   391 QQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSD 455
                       :|....||......|...:.....|.|.|....|||::|:|||||||.:|.|||
Mosquito   403 -----------ASGCGPGGPGGMGGPGTGVGPGGPGGLGPGDDCESDDDGQEIIEEDDESDRPSD 456

  Fly   456 SSSPHGDGN---SKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQ 517
            |:||:.:|:   :||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   457 SASPNSNGSAMQAKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQ 521

  Fly   518 NRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYY--AAARN 580
            |||||||||||||||||||||||||||||||||||||:|.|.|||||||..|....||  :|.|.
Mosquito   522 NRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHEGATGGFVPPPPHPHSQQLYYTTSAGRA 586

  Fly   581 TSPPRPPLSSLV 592
            .|||||||||||
Mosquito   587 GSPPRPPLSSLV 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	55/55 (100%)
Hmx	XP_310605.6	None