Protein Alignment Hmx and unpg

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_308835.5
• Gene: unpg / 1270160
• VectorBaseID: AGAMI1_008945
• Length: 588
• Species: Anopheles gambiae
• Alignment Length: 748
• Identity: 173/748 - (23%)
• Similarity: 236/748 - (31%)
• Gaps: 318/748 - (42%)

  Fly    13 VSSPEPSPLGA---AARDSPLLARSPARSADGSSPPATPTHRSNTPNTAAGTPTTSASGGNHFHH 74
            :|:.:|:|:|:   ...|.......|:.|....:..|....||    ..||:.:.....|:|
Mosquito     4 LSTVQPAPVGSVVCGVTDVKFSRPLPSSSFSIENLIAVKRRRS----AGAGSSSPEIDPGDH--- 61

  Fly    75 SPSGGAVPPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGATHPALLQHALTPTGQQQQQ 139
              .|...|||              :.|           ::.|.:|:        .|..|.|||
Mosquito    62 --HGSCSPPA--------------AGP-----------NVPPGYGS--------LLLETSQQQ-- 89

  Fly   140 QLQVQQQHQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNSKALNHNNTCASAAAAAAAAAVAAA 204
                ||||||.::                                         ||||||..:||
Mosquito    90 ----QQQHQQHYL-----------------------------------------AAAAAAGYSAA 109

  Fly   205 NLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQLPQPGAGG- 268
            .||                       |:||                        |.|..|.:.|
Mosquito   110 MLS-----------------------FSSF------------------------PPLYHPWSTGL 127

  Fly   269 PQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRLP---FHSPTHDSSSTNTT-----ENPP 325
            |                 .||||.:..      |.::|.   ||   |.||..|.:     |..|
Mosquito   128 P-----------------TAGRYLSQA------ANEKLSSLLFH---HHSSGGNKSHPGGIEPCP 166

  Fly   326 S--PTSMSPNNNNNN-SNTTASSNQASKS-----PSHHPL----HPLYHPLGSQQQQQQQQQHQQ 378
            .  |.:..|.:.... ..|..||.:.::|     |:...|    :.:||      .||||||.||
Mosquito   167 GTYPAAEQPQSGGGGVLPTRPSSPRGARSGDKLFPTEVDLLSKVYAVYH------HQQQQQQQQQ 225

  Fly   379 HPQ--------------------QQQHPQQQQQQHPHQPTTP--TSSSSSGGGSSLTHHPHPHLT 421
            .|:                    ...:|.....|..|||.:|  |....|.||........|  |
Mosquito   226 QPRYLTPSSPGTGYTTTGAALEPNGVNPGTGNGQLHHQPQSPGETIDPGSDGGPEDEERTRP--T 288

  Fly   422 GSHGG--------------YLLPSSSNESDEEGE---EIIEEDDGTDGPSDS----SSPHGDGNS 465
            ...||              .|.||...::.:.|:   :...|||.|...|.|    .|..|..||
Mosquito   289 IEDGGESADGSAYSDDISLTLSPSGCGKTTDLGDSDSDACSEDDCTQNSSSSGRAGKSGSGAENS 353

  Fly   466 KRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAE 530
            |.::: ||.|:..|:.:||..|..|:|||.:||:.:|.||:|:|.||||||||||.|||| :.|.
Mosquito   354 KSRRR-RTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR-VKAG 416

  Fly   531 LEAANMAN---------MAHAAQRLVRVPVLYHDGTTA--------------------------- 559
            |.:..:.|         ....|.::| ||:..|....|
Mosquito   417 LNSHGLGNRNASGSGTGTTGTANKIV-VPIPVHVNRFAIRSQHQQMEKMNLVGPKAELRKADLGL 480

  Fly   560 ----GF------------VP---------PPPPHHHPMQYYAAARNTSPPRPPLSSLVXGVG--- 596
                ||            ||         .|.....|....|.|.:.......:.|.| |.|
Mosquito   481 AESGGFERFGLNKHLSKVVPSAEVTSNRVDPAFSAGPTLQAAPAPSEGASNSSIESSVTGGGGAG 545

  Fly   597 --------------CLATAPMSLLKPPNSMAHP 615
                          .|.....||..||:|.:||
Mosquito   546 GGGGAGTAGIGVGFQLGMGVCSLAAPPHSASHP 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	30/55 (55%)
unpg	XP_308835.5	None