Protein Alignment Hmx and Hoxb2

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001386664.1
• Gene: Hoxb2 / 100361765
• RGDID: 2319509
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 379
• Identity: 93/379 - (24%)
• Similarity: 135/379 - (35%)
• Gaps: 106/379 - (27%)

  Fly   278 LGFISQWGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSP-----TSMSPNNNNN 337
            :|||:...:||.     |...:|...:..      ..||...:|..||.|     |..|.....:
  Rat     9 IGFINSQPSLAE-----CLTSFPAVLETF------QTSSIKESTLIPPPPPPLEQTFPSLQLGAS 62

  Fly   338 NSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPT---- 398
            ......|...|...|:..|..||  |:.              |...:.|..::::...:|:
  Rat    63 TLQRPGSQKPAGDGPALRPPPPL--PVA--------------PPAPEFPWMKEKKSAKKPSQSAA 111

  Fly   399 TPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDG 463
            ||:.::||...|.:         ||      ||                   |||   ..|...|
  Rat   112 TPSPAASSVRASGV---------GS------PS-------------------DGP---GLPESGG 139

  Fly   464 NSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQ-- 526
            :..|  :.||.::..|:.:||..|...:||....|..:||.|.|||.|||:||||||.|.|||
  Rat   140 SGSR--RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 202

  Fly   527 -----------LAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAAARN 580
                       |:|:.:|...|.....:..    .|..|....|.|:        |.:.....|.
  Rat   203 HREPPDGEPGGLSAQDDAGEPAEEPTVSPG----DVASHRLREACFL--------PAEAAQGPRG 255

  Fly   581 TSPPRPPLSSLVXGVGCLATAPMSLLKPPNSMAHPPHPQPPPPAPLHMQQRSFL 634
            ..||.||.::| ..||  |::|...:.....:...|.|:...|   ..|...||
  Rat   256 APPPLPPATAL-ESVG--ASSPGCTMLRAGGLQSEPLPEDACP---ERQDSPFL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	25/55 (45%)
Hoxb2	NP_001386664.1	Homeodomain	143..199	CDD:459649	26/57 (46%)