Protein Alignment Hmx and nkx6-2

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_002937836.1
• Gene: nkx6-2 / 100038084
• XenbaseID: XB-GENE-484527
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 239
• Identity: 71/239 - (29%)
• Similarity: 100/239 - (41%)
• Gaps: 66/239 - (27%)

  Fly   326 SPTSMSPNNNNNNSNTT----ASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHP 386
            |.|.::..:|.....||    |..|.:.|:|....|.... |||:
 Frog    18 SSTPLAALHNMAEMKTTLFPYALQNPSFKAPGLSSLSAQI-PLGT-------------------- 61

  Fly   387 QQQQQQHPH-------QPTTPTSSSSSGGGSSLTHHPHPHLTG---SHGGYLLPSSSNESDEEGE 441
                   ||       :|...|..||:...|||     |.:.|   |.|.|..|::.:...:...
 Frog    62 -------PHGISDILSRPLGATLGSSANLLSSL-----PRINGLATSTGMYFNPAAVSRYPKPLA 114

  Fly   442 E-----------IIEEDDGTDGPSDSSSPHG-----DGNSKRKKKTRTVFSRAQVFQLESTFDLK 490
            |           :::.....|......|..|     ||   :||.:|..||..|:|.||.||:..
 Frog   115 ELPGRAPIFWPGVMQGSPWRDPRLGCPSQAGMVLDKDG---KKKHSRPTFSGQQIFALEKTFEQT 176

  Fly   491 RYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAA 534
            :||:..|||.||.||.:||:|||:||||||.||:::.|||:..|
 Frog   177 KYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMATA 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	32/55 (58%)
nkx6-2	XP_002937836.1	Homeodomain	153..211	CDD:459649	33/57 (58%)