Protein Alignment Prx3 and Prdx6

DIOPT Version :9

• Sequence 1: NP_524387.1
• Gene: Prx3 / 42109
• FlyBaseID: FBgn0038519
• Length: 234
• Species: Drosophila melanogaster
• Sequence 2: NP_446028.1
• Gene: Prdx6 / 94167
• RGDID: 71005
• Length: 224
• Species: Rattus norvegicus
• Alignment Length: 203
• Identity: 53/203 - (26%)
• Similarity: 99/203 - (48%)
• Gaps: 25/203 - (12%)

  Fly    46 APDFKGLAVVDNSFQEVKLEDYRG-KYLVLFFYPLDFTFVCPTEIVAFSERIKEFHDINTEVLGV 109
            ||:|:    .:.:...::..|:.| .:.:||.:|.|||.||.||:...::...||...|.:::.:
  Rat    11 APNFE----ANTTIGHIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly   110 SVDSHFSHLTWC-NVDRKNGG--VGQLKYPLLSDLTKKISADYDVLL--------DKEG--ISLR 161
            |:||...|..|. :::..||.  ..:|.:|::.|..:    |..:||        |::|  ::.|
  Rat    72 SIDSVEDHFAWSKDINAYNGAAPTEKLPFPIIDDKDR----DLAILLGMLDPAEKDEKGMPVTAR 132

  Fly   162 GTFIIDPNGILRQYSINDLPVGRSVDEVLRLIKAFQFVEQHGEVCPANWNPNSNPATIK--PDVE 224
            ..||..|:..|:...:.....||:.||:||::.:.|....:....|.:|....:...:.  |: |
  Rat   133 VVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTASNPVATPVDWKKGESVMVLPTLPE-E 196

  Fly   225 ESKKYFSK 232
            |:|:.|.|
  Rat   197 EAKQLFPK 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	AhpC	40..233	CDD:223527	53/203 (26%)
		PRX_Typ2cys	42..212	CDD:239313	47/179 (26%)
		1-cysPrx_C	195..232	CDD:287400	8/38 (21%)
Prdx6	NP_446028.1	AhpC	5..200	CDD:223527	50/197 (25%)
		PRX_1cys	7..222	CDD:239314	53/203 (26%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000269|PubMed:19700648	31..40		2/8 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.710