DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx3 and TSA2

DIOPT Version :9

Sequence 1:	NP_524387.1	Gene:	Prx3 / 42109	FlyBaseID:	FBgn0038519	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_010741.1	Gene:	TSA2 / 852064	SGDID:	S000002861	Length:	196	Species:	Saccharomyces cerevisiae

Alignment Length:	189	Identity:	108/189 - (57%)
Similarity:	141/189 - (74%)	Gaps:	2/189 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VQQPAPDFKGLAVVDNSFQEVKLEDYRGKYLVLFFYPLDFTFVCPTEIVAFSERIKEFHDINTEV 106
            ||:.||.||..||||..|:|:.||.|:|||:||.|.||.|:|||||||||||:..|:|.|...:|
Yeast     5 VQKQAPPFKKTAVVDGIFEEISLEKYKGKYVVLAFVPLAFSFVCPTEIVAFSDAAKKFEDQGAQV 69

  Fly   107 LGVSVDSHFSHLTWCNVDRKNGGVGQLKYPLLSDLTKKISADYDVLLDKEGISLRGTFIIDPNGI 171
            |..|.||.:|.|.|.|:.||:||:|.:|.|||:|....:|.||.||::||||:|||.|||||.||
Yeast    70 LFASTDSEYSLLAWTNLPRKDGGLGPVKVPLLADKNHSLSRDYGVLIEKEGIALRGLFIIDPKGI 134

  Fly   172 LRQYSINDLPVGRSVDEVLRLIKAFQFVEQHGEVCPANWNPNSNPATIKPDVEESKKYF 230
            :|..:||||.|||:|:|.|||::.||:.:::|.|.|.||.|.:  |||||||::||:||
Yeast   135 IRHITINDLSVGRNVNEALRLVEGFQWTDKNGTVLPCNWTPGA--ATIKPDVKDSKEYF 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	AhpC	40..233	CDD:223527	108/189 (57%)
		PRX_Typ2cys	42..212	CDD:239313	96/169 (57%)
		1-cysPrx_C	195..232	CDD:287400	19/36 (53%)
TSA2	NP_010741.1	PRX_Typ2cys	5..176	CDD:239313	96/170 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346742
Domainoid	1	1.000	161	1.000	Domainoid score	I848
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4944
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54000
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X272
TreeFam	0	0.000	Not matched by this tool.
	10	9.650