DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx3 and Prdx4

DIOPT Version :9

Sequence 1:	NP_524387.1	Gene:	Prx3 / 42109	FlyBaseID:	FBgn0038519	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_001300640.1	Gene:	Prdx4 / 53381	MGIID:	1859815	Length:	275	Species:	Mus musculus

Alignment Length:	186	Identity:	107/186 - (57%)
Similarity:	140/186 - (75%)	Gaps:	5/186 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 IAARLLHQTAPLAAVRVQQPAPDFKGLAVVDNSFQEVKLEDYRGKYLVLFFYPLDFTFVCPTEIV 90
            :|...||    |:..::.:|||.::|.||::..|:|:||.||||||||.|||||||||||||||:
Mouse    72 VADHSLH----LSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEII 132

  Fly    91 AFSERIKEFHDINTEVLGVSVDSHFSHLTWCNVDRKNGGVGQLKYPLLSDLTKKISADYDVLLDK 155
            ||.:||:||..|||||:..||||.|:||.|.|..|:.||:|.::.||||||..:||.||.|.|:.
Mouse   133 AFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLED 197

  Fly   156 EGISLRGTFIIDPNGILRQYSINDLPVGRSVDEVLRLIKAFQFVEQHGEVCP-ANW 210
            .|.:|||.||||..|:|||.::|||||||||||.|||::|||:.::|||..| ::|
Mouse   198 SGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSW 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	AhpC	40..233	CDD:223527	103/172 (60%)
		PRX_Typ2cys	42..212	CDD:239313	103/170 (61%)
		1-cysPrx_C	195..232	CDD:287400	8/17 (47%)
Prdx4	NP_001300640.1	PRX_Typ2cys	84..254	CDD:239313	103/170 (61%)
Prdx4	NP_001300640.1	AhpC-TSA	84..217	CDD:278975	80/132 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54000
OrthoDB	1	1.010	-	-		D1326484at2759
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X272
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730