DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx3 and prdx3

DIOPT Version :9

Sequence 1:	NP_524387.1	Gene:	Prx3 / 42109	FlyBaseID:	FBgn0038519	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_001013478.3	Gene:	prdx3 / 373079	ZFINID:	ZDB-GENE-030826-18	Length:	250	Species:	Danio rerio

Alignment Length:	227	Identity:	136/227 - (59%)
Similarity:	172/227 - (75%)	Gaps:	9/227 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VPLMGKAILSQQKQIAARLLHQTA--PLAAVR----VQQPAPDFKGLAVVDNSFQEVKLEDYRGK 70
            ||..|.:::...:.:|. :..|.|  .::|.|    |.|.||.|||.||::..|:|:.|.|::||
Zfish    25 VPRNGASVIRAPQPLAC-IAAQKACFSISAARWAPAVTQAAPHFKGTAVINGEFKEISLGDFKGK 88

  Fly    71 YLVLFFYPLDFTFVCPTEIVAFSERIKEFHDINTEVLGVSVDSHFSHLTWCNVDRKNGGVGQLKY 135
            |||||||||||||||||||||||::..||||:|..|:||||||||:||.|.|..||:||:|:::.
Zfish    89 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCAVVGVSVDSHFTHLAWTNTPRKSGGLGKIQI 153

  Fly   136 PLLSDLTKKISADYDVLLDKEGISLRGTFIIDPNGILRQYSINDLPVGRSVDEVLRLIKAFQFVE 200
            |||:||||::|.||.|||:..||:|||.||||||||:|..|:|||||||||:|.|||:|||||||
Zfish   154 PLLADLTKQVSRDYGVLLEGPGIALRGLFIIDPNGIVRHMSVNDLPVGRSVEETLRLVKAFQFVE 218

  Fly   201 QHGEVCPANWNPNSNPATIKPDVEESKKYFSK 232
            .|||||||:|.|.|  .||||..:.||:||.|
Zfish   219 THGEVCPASWTPKS--PTIKPTPDGSKEYFEK 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	AhpC	40..233	CDD:223527	129/197 (65%)
		PRX_Typ2cys	42..212	CDD:239313	117/169 (69%)
		1-cysPrx_C	195..232	CDD:287400	24/36 (67%)
prdx3	NP_001013478.3	PRX_Typ2cys	60..230	CDD:239313	117/169 (69%)
prdx3	NP_001013478.3	PTZ00253	64..250	CDD:140280	126/187 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	194	1.000	Domainoid score	I3127
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4944
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2945
OMA	1	1.010	-	-		QHG54000
OrthoDB	1	1.010	-	-		D1326484at2759
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	1	1.000	-	-		oto40347
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	LDO	PTHR42801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6659
SonicParanoid	1	1.000	-	-		X272
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870