DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx3 and Prdx3

DIOPT Version :9

Sequence 1:	NP_524387.1	Gene:	Prx3 / 42109	FlyBaseID:	FBgn0038519	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_031478.1	Gene:	Prdx3 / 11757	MGIID:	88034	Length:	257	Species:	Mus musculus

Alignment Length:	191	Identity:	130/191 - (68%)
Similarity:	153/191 - (80%)	Gaps:	2/191 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VQQPAPDFKGLAVVDNSFQEVKLEDYRGKYLVLFFYPLDFTFVCPTEIVAFSERIKEFHDINTEV 106
            |.|.||.|||.|||:..|:|:.|:|::|||||||||||||||||||||||||::..||||:|.||
Mouse    66 VTQHAPYFKGTAVVNGEFKELSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEV 130

  Fly   107 LGVSVDSHFSHLTWCNVDRKNGGVGQLKYPLLSDLTKKISADYDVLLDKEGISLRGTFIIDPNGI 171
            :.||||||||||.|.|..|||||:|.:...||||:||:||.||.|||:..||:|||.|||||||:
Mouse   131 VAVSVDSHFSHLAWINTPRKNGGLGHMNITLLSDITKQISRDYGVLLESAGIALRGLFIIDPNGV 195

  Fly   172 LRQYSINDLPVGRSVDEVLRLIKAFQFVEQHGEVCPANWNPNSNPATIKPDVEESKKYFSK 232
            ::..|:|||||||||:|.|||:|||||||.|||||||||.|.|  .||||....||:||.|
Mouse   196 VKHLSVNDLPVGRSVEETLRLVKAFQFVETHGEVCPANWTPES--PTIKPSPTASKEYFEK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	AhpC	40..233	CDD:223527	130/191 (68%)
		PRX_Typ2cys	42..212	CDD:239313	119/169 (70%)
		1-cysPrx_C	195..232	CDD:287400	25/36 (69%)
Prdx3	NP_031478.1	PRX_Typ2cys	66..236	CDD:239313	119/169 (70%)
Prdx3	NP_031478.1	PTZ00253	70..252	CDD:140280	125/183 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	192	1.000	Domainoid score	I3208
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4944
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2963
Isobase	1	0.950	-	0	Normalized mean entropy	S305
OMA	1	1.010	-	-		QHG54000
OrthoDB	1	1.010	-	-		D1326484at2759
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	1	1.000	-	-		oto92848
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	LDO	PTHR42801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6659
SonicParanoid	1	1.000	-	-		X272
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.820