Protein Alignment Prx3 and PRDX4

DIOPT Version :10

• Sequence 1: NP_524387.1
• Gene: Prx3 / 42109
• FlyBaseID: FBgn0038519
• Length: 234
• Species: Drosophila melanogaster
• Sequence 2: NP_006397.1
• Gene: PRDX4 / 10549
• HGNCID: 17169
• Length: 271
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 122/207 - (58%)
• Similarity: 152/207 - (73%)
• Gaps: 6/207 - (2%)

  Fly    26 IAARLLHQTAPLAAVRVQQPAPDFKGLAVVDNSFQEVKLEDYRGKYLVLFFYPLDFTFVCPTEIV 90
            :|...||    |:..::.:|||.::|.||:|..|:|:||.||||||||.|||||||||||||||:
Human    69 VADHSLH----LSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEII 129

  Fly    91 AFSERIKEFHDINTEVLGVSVDSHFSHLTWCNVDRKNGGVGQLKYPLLSDLTKKISADYDVLLDK 155
            ||.:|::||..|||||:..||||.|:||.|.|..|:.||:|.::.|||||||.:||.||.|.|:.
Human   130 AFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLED 194

  Fly   156 EGISLRGTFIIDPNGILRQYSINDLPVGRSVDEVLRLIKAFQFVEQHGEVCPANWNPNSNPATIK 220
            .|.:|||.||||..|||||.::|||||||||||.|||::|||:.::|||||||.|.|.|.  ||.
Human   195 SGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSE--TII 257

  Fly   221 PDVEESKKYFSK 232
            ||.....|||.|
Human   258 PDPAGKLKYFDK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prx3	NP_524387.1	PRX_Typ2cys	42..212	CDD:239313	108/169 (64%)
		1-cysPrx_C	195..232	CDD:431271	20/36 (56%)
PRDX4	NP_006397.1	PRX_Typ2cys	81..252	CDD:239313	108/170 (64%)