DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5823 and UBC6

DIOPT Version :9

Sequence 1:	NP_001262669.1	Gene:	CG5823 / 42105	FlyBaseID:	FBgn0038515	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_011026.3	Gene:	UBC6 / 856837	SGDID:	S000000902	Length:	250	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	110/267 - (41%)
Similarity:	154/267 - (57%)	Gaps:	25/267 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AVSRMKQDYMRLKRDPLPYITAEPLPNNILEWHYCVKGPEDSPYYGGYYHGTLLFPREFPFKPPS 79
            |..|:.::|..:..:|.|||.|.|..:|||||||.:.||.|:||.||.|||||.||.::|:|||:
Yeast     6 AHKRLTKEYKLMVENPPPYILARPNEDNILEWHYIITGPADTPYKGGQYHGTLTFPSDYPYKPPA 70

  Fly    80 IYMLTPNGRFKTNTRLCLSISDFHPDTWNPTWCVGTILTGLLSFMLESTPTLGSIESSNYDKQMF 144
            |.|:|||||||.|||||||:||:|||||||.|.|.|||.||||||.....|.|||.:|::.|:..
Yeast    71 IRMITPNGRFKPNTRLCLSMSDYHPDTWNPGWSVSTILNGLLSFMTSDEATTGSITTSDHQKKTL 135

  Fly   145 AQKSLAFN-LRNTNFCELFPEIVEEIKQRLRGTQAAAAVDGPAAN-GVKRSNGLANGASLASADG 207
            |:.|:::| .:|..|..:|||:|:|..:.|   :.....:|.||| |.:..:.....|
Yeast   136 ARNSISYNTFQNVRFKLIFPEVVQENVETL---EKRKLDEGDAANTGDETEDPFTKAA------- 190

  Fly   208 NLAVGGLANPLNAADAIDGGAAGQADLASGGGAAVQNSARNSYLNWQSVY-SNLVIIICFAIFAL 271
            ...|..|...|:..|.|      :|:      .|::.|..||..:.:... |:.::.|..|||..
Yeast   191 KEKVISLEEILDPEDRI------RAE------QALRQSENNSKKDGKEPNDSSSMVYIGIAIFLF 243

  Fly   272 IVNYVIK 278
            :|...:|
Yeast   244 LVGLFMK 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5823	NP_001262669.1	UBCc	16..129	CDD:238117	69/112 (62%)
UBC6	NP_011026.3	COG5078	1..154	CDD:227410	81/147 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344101
Domainoid	1	1.000	163	1.000	Domainoid score	I835
eggNOG	1	0.900	-	-		E1_KOG0894
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10975
Inparanoid	1	1.050	193	1.000	Inparanoid score	I895
Isobase	1	0.950	-	0	Normalized mean entropy	S649
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004329
OrthoInspector	1	1.000	-	-		oto99105
orthoMCL	1	0.900	-	-		OOG6_101978
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1584
SonicParanoid	1	1.000	-	-		X3056
TreeFam	1	0.960	-	-
	15	14.730