DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and IL1RL1

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:NP_057316.3 Gene:IL1RL1 / 9173 HGNCID:5998 Length:556 Species:Homo sapiens


Alignment Length:309 Identity:77/309 - (24%)
Similarity:110/309 - (35%) Gaps:58/309 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   268 CNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWIC----QASNQFGE 328
            |..||.|.....|| .|.:....|.....||..|..||....|...|:|.:.|    ...|:.|.
Human    36 CPRQGKPSYTVDWY-YSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGY 99

  Fly   329 QRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSAID------AIDWLHNGKPLQANNAL 387
            ..:.|....:.......|....:..|...:...|.|    ||      .::|..|.:.||.:   
Human   100 ANVTI
YKKQSDCNVPDYLMYSTVSGSEKNSKIYCPT----IDLYNWTAPLEWFKNCQALQGS--- 157

  Fly   388 TTGRDNIRFLS-KSSLLVQNVGRRDRGVYQC-LVENQRA---SAQAMAELKLGDTVPELIYTFI- 446
                   |:.: ||.|::.||...|.|.|.| .:.|:..   |..|.....:.|.....::..| 
Human   158 -------RYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIG 215

  Fly   447 --EQN----VRPGPLISLKCSASGSPPPQF----AWLLDSQPIMDV---------SLHHRFAIG- 491
              .||    |..|...:|.|||......||    .|.|:...|.|.         ..:..|:.| 
Human   216 APAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGL 280

  Fly   492 QFVDMSGDVISHLNISHVRPDDGGL-YKCVASNSMGSVQHSARLNVYGP 539
            ..:||.      |.|:.|:.:|..| |.|:|.|..|..:|:.||:...|
Human   281 ACLDMV------LRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNP 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352 20/72 (28%)
Ig 264..334 CDD:143165 19/69 (28%)
I-set 345..433 CDD:254352 23/98 (23%)
Ig 358..431 CDD:143165 21/83 (25%)
Ig 456..533 CDD:143165 25/91 (27%)
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
IL1RL1NP_057316.3 Ig 16..104 CDD:299845 19/68 (28%)
IG_like 21..104 CDD:214653 19/68 (28%)
Ig2_IL1R_like 118..204 CDD:143234 22/99 (22%)
IG_like 120..197 CDD:214653 21/90 (23%)
Flexible linker 198..211 1/12 (8%)
TIR 380..535 CDD:279864
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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