DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dscam3 and Treml2

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:XP_001059150.1 Gene:Treml2 / 680844 RGDID:1587039 Length:330 Species:Rattus norvegicus


Alignment Length:256 Identity:50/256 - (19%)
Similarity:86/256 - (33%) Gaps:84/256 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   822 EQSARNISSRRNDPVTLDCHAKG------------------DEPITIGWTQNNGRIDLNNFRFSI 868
            |:..|.:..|..:.:::.|..|.                  :...|..|.:...        :|:
  Rat    28 EKLYRKVQRREGETLSVQCSYKNRRNLVEAKSWCKVKRKKCEHSFTRSWVRGPS--------YSM 84

  Fly   869 AEMKTEKGVDSQLTIGHSDRHDSGVYRCI---AENPY---GRAEQIIFLAVQERPDTPSHLEIFE 927
            .:....|.|  ::|:......|||.|.|:   |.|.|   |...::......||...|:||    
  Rat    85 RDDTKAKVV--RITMEALRVQDSGRYWCMRNTAGNLYPLVGFQLEVYPALTTERNVPPTHL---- 143

  Fly   928 VGSRTVKLSWRRPFDG--NSPVLSYLVQYQALKYLQSHGSLAAAGGDWNGHVINVSLPSTSISRS 990
              :.|:|       ||  |:|:..::...|.                   |:.:...|.|:....
  Rat   144 --TNTLK-------DGFANTPMDEFVTTSQV-------------------HMSDTGDPFTTNVTV 180

  Fly   991 YDSDLRESAIVAGLTPAT-----TFLIRMQAINEIERSAYTEAIVLKTQEEAPTEAPSNVQ 1046
            :.|.|.  .:.:|.|..|     :|......|.|.|||         |:.:..|.:||:.:
  Rat   181 FSSGLH--TLASGTTAPTPVTRYSFADTSGTITETERS---------TESQPATVSPSHTR 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352
Ig 264..334 CDD:143165
I-set 345..433 CDD:254352
Ig 358..431 CDD:143165
Ig 456..533 CDD:143165
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352 20/114 (18%)
Ig 838..920 CDD:299845 19/105 (18%)
FN3 917..1033 CDD:238020 24/122 (20%)
FN3 1040..1142 CDD:238020 2/7 (29%)
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
Treml2XP_001059150.1 Ig 32..128 CDD:416386 19/105 (18%)
FR1 33..46 CDD:409353 1/12 (8%)
Ig strand A' 33..38 CDD:409353 0/4 (0%)
Ig strand B 40..47 CDD:409353 0/6 (0%)
CDR1 47..56 CDD:409353 1/8 (13%)
Ig strand C 56..61 CDD:409353 0/4 (0%)
FR2 57..61 CDD:409353 0/3 (0%)
CDR2 62..78 CDD:409353 2/15 (13%)
Ig strand C' 69..72 CDD:409353 0/2 (0%)
Ig strand C' 76..78 CDD:409353 1/1 (100%)
FR3 81..112 CDD:409353 9/40 (23%)
Ig strand D 81..87 CDD:409353 1/13 (8%)
Ig strand E 91..99 CDD:409353 3/9 (33%)
Ig strand F 105..112 CDD:409353 4/6 (67%)
CDR3 113..123 CDD:409353 3/9 (33%)
FR4 123..128 CDD:409353 1/4 (25%)
Ig strand G 123..128 CDD:409353 1/4 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.