DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and LOC563995

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_021327870.1	Gene:	LOC563995 / 563995	-ID:	-	Length:	280	Species:	Danio rerio

Alignment Length:	281	Identity:	58/281 - (20%)
Similarity:	98/281 - (34%)	Gaps:	97/281 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 TTQKPVMEIHVERGNDVHLPCNIQGNPFPI----FTWYRVSDSAA---LYPIPSSQRVILSRTL- 304
            |.:.|...:....|:.|.|||.:. ...|:    ..|.| :||..   ||....|:..:..:..
Zfish    11 TVRGPSAPLSAPLGSSVVLPCYVD-EALPVEDLEVEWRR-ADSETLIHLYQDGESRAEVQQQDYH 73

  Fly   305 ----------------LLIKNADERDAGKWICQASNQ--FGEQRIEIR----------------- 334
                            |.:.|...:|.|::.|:..:|  .|:...:|:
Zfish    74 DRAHFFTEEIQHGNFSLRLDNLTAQDEGEYRCRVHSQQDSGQTVAQIKDVERLLVSGSDKSISAY 138

  Fly   335 ----LSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSAIDAIDWLHNGKPL----QANNALTTG- 390
                |::|.:|:.||.|:          :|.          :.|:..|:.|    |.|..:...
Zfish   139 VGGDLTLNCFVNSHITPE----------HFE----------VSWIRTGEILVLLFQNNETILEAA 183

  Fly   391 ----RDNIRFLSKS------SLLVQNVGRRDRGVYQCLVENQRASAQAMAEL-KLGDTVPELIYT 444
                |..:.|.:..      ||.:::|...|:|||.|.|.....||.|..|| :||.:...::
Zfish   184 HEKYRGRVEFFTAEIPKGNFSLRLKSVRIEDKGVYMCQVFAGDLSANATVELERLGFSAVHIM-- 246

  Fly   445 FIEQNVRPGPLISLKCSASGS 465
                      ::.|...||||
Zfish   247 ----------MMILCICASGS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352	24/135 (18%)
		Ig	264..334	CDD:143165	19/95 (20%)
		I-set	345..433	CDD:254352	24/103 (23%)
		Ig	358..431	CDD:143165	20/87 (23%)
		Ig	456..533	CDD:143165	5/10 (50%)
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
LOC563995	XP_021327870.1	Ig	24..121	CDD:325142	20/98 (20%)
LOC563995	XP_021327870.1	Ig	140..235	CDD:325142	26/114 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910