DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and mxra8b

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	NP_001073429.3	Gene:	mxra8b / 556385	ZFINID:	ZDB-GENE-061013-368	Length:	434	Species:	Danio rerio

Alignment Length:	359	Identity:	66/359 - (18%)
Similarity:	119/359 - (33%)	Gaps:	138/359 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 TQKPVMEIHVER-------GNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTLLL 306
            ||..:..:.||.       |:||.|||:   |...::...|:.|         .|||:   ...|
Zfish    18 TQNSIPSVVVEARNITVPVGSDVVLPCH---NQRMVWRQDRLRD---------RQRVV---HWDL 67

  Fly   307 IKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSAIDA 371
            |:|..:                           |....||...    ||||
Zfish    68 IRNQPD---------------------------YTVERILDMF----SGGT-------------- 87

  Fly   372 IDWLHN----GKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQRASAQAMAEL 432
             :.|:|    |:...|.:|.:.|        ..||::.||...|:|:|.|.:.:.........::
Zfish    88 -ERLYNDYNKGRVTIAKDAFSDG--------NFSLVINNVDMNDKGIYTCNLHHHYCKVHQSVQM 143

  Fly   433 KLGDT------------------------------VPELIYTFIEQNVRPGPLISLKCSASGSPP 467
            :|..|                              :...::|..:::.....::.....|.|...
Zfish   144 QLNVTKSPRKEKRVWDGEKAVFVVLVGKSVVLPCVIRRQLWTDSQRDEGQQQVVHWDWQAPGVTR 208

  Fly   468 PQFAWLLDS--------------QPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYK 518
            .:...|:|.              |..|::|. ..|::|.|         .|::.:::|.|.||:.
Zfish   209 DRAERLIDMYASGEKRQYGPLYLQKKMNISA-DAFSLGDF---------SLSLHNIQPADKGLFS 263

  Fly   519 CVASNSMGSVQHSARLN--VYGPPYVRAIGPIKA 550
            |...:....: |..|:.  :.||. |:|:.|:::
Zfish   264 CHLHHHYCGL-HERRIYRLILGPS-VQALPPVRS 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352	19/94 (20%)
		Ig	264..334	CDD:143165	13/69 (19%)
		I-set	345..433	CDD:254352	20/91 (22%)
		Ig	358..431	CDD:143165	14/76 (18%)
		Ig	456..533	CDD:143165	17/90 (19%)
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
mxra8b	NP_001073429.3	V-set	30..148	CDD:311561	37/186 (20%)
mxra8b	NP_001073429.3	IGv	172..264	CDD:214650	16/101 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910