DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and RGD1562667

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_577143.3	Gene:	RGD1562667 / 501742	RGDID:	1562667	Length:	222	Species:	Rattus norvegicus

Alignment Length:	119	Identity:	31/119 - (26%)
Similarity:	50/119 - (42%)	Gaps:	28/119 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1466 GGAPLQGYTISYHTAGESWSITELLPENNAFTISGLKCGNQYIIKMS----AHNMVGSGVASEEI 1526
            |..||.|.:....|.|||.|:|....|       |.|...:|..:.|    ..::|.:|.:.|:.
  Rat    21 GCVPLHGPSSVTGTVGESLSVTCQYEE-------GFKTNKKYWCRGSLVLLCEDIVMTGGSEEDR 78

  Fly  1527 NVWTKGKASQAPNANELIATNATCVNLKLSSWQNGG---CSI------HHFSIE 1571
            |    |:.|...:.:.||.|    |.|:..:.::.|   |::      |.|.|:
  Rat    79 N----GRVSIRDDPDNLIFT----VTLESLTMEDAGTYMCAVDIPLIDHSFGID 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020	19/67 (28%)
		FN3	1542..1620	CDD:238020	10/39 (26%)
RGD1562667	XP_577143.3	IG_like	28..123	CDD:214653	26/109 (24%)
RGD1562667	XP_577143.3	Ig_pIgR	31..132	CDD:143193	27/109 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910