DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and DIP-gamma

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:NP_651649.1 Gene:DIP-gamma / 43417 FlyBaseID:FBgn0039617 Length:413 Species:Drosophila melanogaster


Alignment Length:388 Identity:85/388 - (21%)
Similarity:145/388 - (37%) Gaps:89/388 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   518 KCVASNSMGSVQH--SARLNVYGPPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQE-- 578
            || .|.|..:..|  |::|:. .|.::..|..:...||.:.|:.|........::.|.:|..:  
  Fly    18 KC-GSGSTQNQHHESSSQLDP-DPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTV 80

  Fly   579 ------LTTSN------HYELASVADGGQLVIKNVEPGRDQGIYTCIV-----RSRAGEEARRDM 626
                  :.|.|      |.::.:    .:|.|..:... |:|.|.|.:     :.:.|       
  Fly    81 LALQGRVVTHNARISVMHQDMHT----WKLKISKLRES-DRGCYMCQINTSPMKKQVG------- 133

  Fly   627 QLNVNSPPVI--EPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSI-----PSSLQITEK 684
            .::|..||.|  |.......:|||..|.:||..:....| ..:|:::|..:     |.|.::.:.
  Fly   134 CIDVQVPPDIINEESSADLAVQEGEDATLTCKATGNPQP-RVTWRREDGEMILIRKPGSRELMKV 197

  Fly   685 KEEFYSLLVFKDISARHSGKYTCYASN-AAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISIN 748
            :....|.|....:..|..|.|.|.||| ....|:....|.|:.||..|.........||:.:.:.
  Fly   198 ESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLE 262

  Fly   749 CEAEGYPIPTITWFKG--QGKGSKDFKPLSMRNHS--------------------------LLLN 785
            |:.|..|.|...|.||  ...|.......|:.:.|                          |::.
  Fly   263 CQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVR 327

  Fly   786 LATDNDEGYYMCQATNEIGAGLKKTIRI---------------NVNEPARFEQSARNISSRRN 833
            ..:.:|.|.|.|.:||.:|.. :.|:|:               ::|.....|::||| :.|.|
  Fly   328 SFSPSDVGTYHCVSTNSLGRA-EGTLRLYEIKLHPGASASNDDHLNYIGGLEEAARN-AGRSN 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352
Ig 264..334 CDD:143165
I-set 345..433 CDD:254352
Ig 358..431 CDD:143165
Ig 456..533 CDD:143165 6/16 (38%)
IGc2 553..619 CDD:197706 14/84 (17%)
I-set 634..724 CDD:254352 25/97 (26%)
ig 645..712 CDD:278476 20/72 (28%)
IG_like 734..815 CDD:214653 22/123 (18%)
Ig 745..815 CDD:299845 20/112 (18%)
I-set 820..913 CDD:254352 6/14 (43%)
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
DIP-gammaNP_651649.1 IG_like 47..139 CDD:214653 17/103 (17%)
Ig 47..129 CDD:299845 15/86 (17%)
Ig 140..238 CDD:299845 26/98 (27%)
IG_like 247..355 CDD:214653 22/108 (20%)
Ig 256..351 CDD:299845 19/95 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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