DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and LSAMP

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:NP_001305844.1 Gene:LSAMP / 4045 HGNCID:6705 Length:361 Species:Homo sapiens


Alignment Length:314 Identity:72/314 - (22%)
Similarity:125/314 - (39%) Gaps:43/314 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   645 LQEGGRAQITCAVSSGDMPIYFSWKK---------DDSSIPSSLQITEKKEEFYSLLVFKDISAR 700
            :::|..|.:.|.|...:..:  :|..         |..|:...:::.::....|||.:.| :...
Human    43 VRQGDTAILRCVVEDKNSKV--AWLNRSGIIFAGHDKWSLDPRVELEKRHSLEYSLRIQK-VDVY 104

  Fly   701 HSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITW---- 761
            ..|.|||..............|.|:|.|:......|..:..|:.:::.|.|.|.|.|.|||    
Human   105 DEGSYTCSVQTQHEPKTSQVYLIV
QVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLT 169

  Fly   762 -----FKGQGKGSKDFKPLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARF 821
                 |:|:            ..:..:|.: |....|.|.|:|.||:.:...|.:::.||.|...
Human   170 PTGREFEGE------------EEYLEILGI-TREQSGKYECKAANEVSSADVKQVKVTV
NYPPTI 221

  Fly   822 EQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHS 886
            .:|..| .:......:|.|.|.........|.:::.||:..|.    .|:|:.:| .|.||:.:.
Human   222 TESKSN-EATTGRQASLKCEASAVPAPDFEWYRDDTRINSANG----LEIKSTEG-QSSLTVTNV 280

  Fly   887 DRHDSGVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIFEVGSRTVKLSWRRP 940
            .....|.|.|:|.|..|.....:.|..:..|..|..::  |:|: ||....:.|
Human   281 TEEHYGNYTCVAANKLGVTNASLVLFKRVLPTIPHPIQ--EIGT-TVHFKQKGP 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352
Ig 264..334 CDD:143165
I-set 345..433 CDD:254352
Ig 358..431 CDD:143165
Ig 456..533 CDD:143165
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352 16/87 (18%)
ig 645..712 CDD:278476 15/75 (20%)
IG_like 734..815 CDD:214653 21/89 (24%)
Ig 745..815 CDD:299845 19/78 (24%)
I-set 820..913 CDD:254352 22/92 (24%)
Ig 838..920 CDD:299845 21/81 (26%)
FN3 917..1033 CDD:238020 7/24 (29%)
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
LSAMPNP_001305844.1 Ig 38..128 CDD:386229 16/87 (18%)
Ig 132..215 CDD:386229 22/95 (23%)
Ig_3 219..294 CDD:372822 19/80 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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