DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and ImpL2

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster


Alignment Length:352 Identity:66/352 - (18%)
Similarity:114/352 - (32%) Gaps:120/352 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 ILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAVMLQVKELSKNL 244
            :|...::.|.||.|.|....:....|:.:|:               |:.|:.|......:.:|. 
  Fly    15 LLFGSIATVRGRAVDLVDDSNDVDNSIEAEE---------------EKPRNRAFEADWLKFTKT- 63

  Fly   245 APRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTLLLIKN 309
                   |..::....|..:.:.|.:.|:..|...|       .:..:|.|:             
  Fly    64 -------PPTKLQQADGATIEIVCEMMGSQVPSIQW-------VVGHLPRSE------------- 101

  Fly   310 ADERDAGKWICQASNQFGEQR----IEIRLSVNSYVSVHILPQVQIVNSGGTANFNCT-TTGSAI 369
            .|:.|        |||..|:.    :.:|   :|::..|:|.:.:        .:.|. .|||  
  Fly   102 LDDLD--------SNQVAEEAPSAIVRVR---SSHIIDHVLSEAR--------TYTCVGRTGS-- 145

  Fly   370 DAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQRASAQAMAELKL 434
                     |.:.|:.                                :|...|:|.....:...
  Fly   146 ---------KTIYAST--------------------------------VVHPPRSSRLTPEKTYP 169

  Fly   435 GDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGD 499
            |...|.:|||........|..|.|.|.....|..:..||.:....:.....||      |..:||
  Fly   170 GAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHR------VLANGD 228

  Fly   500 VISHLNISHVRPDDGGLYKCVASNSMG 526
            ::    ||.::.:|.|.|||:|.|.:|
  Fly   229 LL----ISEIKWEDMGNYKCIARNVVG 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352 15/94 (16%)
Ig 264..334 CDD:143165 12/73 (16%)
I-set 345..433 CDD:254352 10/88 (11%)
Ig 358..431 CDD:143165 9/73 (12%)
Ig 456..533 CDD:143165 21/71 (30%)
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 21/73 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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