Protein Alignment Dscam3 and AgaP_AGAP010242

DIOPT Version :9

• Sequence 1: NP_996226.2
• Gene: Dscam3 / 42103
• FlyBaseID: FBgn0261046
• Length: 2087
• Species: Drosophila melanogaster
• Sequence 2: XP_554155.3
• Gene: AgaP_AGAP010242 / 3292147
• VectorBaseID: AGAP010242
• Length: 919
• Species: Anopheles gambiae
• Alignment Length: 904
• Identity: 204/904 - (22%)
• Similarity: 335/904 - (37%)
• Gaps: 193/904 - (21%)

  Fly   439 PELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISH 503
            |.:|...|:..|......:|.|.|.|.|.|...|..|..|:..:...||.|:     .:|.:...
Mosquito    19 PRIIEHPIDTTVPRHEPATLNCKAEGIPQPTIQWYKDGAPLKILQGSHRIAL-----PAGGLFFL 78

  Fly   504 LNISHVRPDDGGLYKCVASNSMGSVQ-HSARLNV--------YGPPYVRAIGPIKAVAGEDIIVH 559
            ..::..|..|.|:|.|.|.|..|..: .:|.|.|        ..|.:.|      ...||.:::.
Mosquito    79 KVVNSRRESDAGVYWCEARNENGIARSRNATLQVAVLREEFRLEPQHTR------VAQGETVLLE 137

  Fly   560 C-PFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEAR 623
            | |..|.|...:.|.|..|:|.......: .:.|||.|.|::|.. .|:|.|.||.::..|....
Mosquito   138 CGPPKGIPEPTLWWRKNGQKLEVEASKRI-RIVDGGNLAIQDVRQ-TDEGQYQCIAKNLVGVRES 200

  Fly   624 RDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDS--SIP-SSLQITEKK 685
            ....|.|:..|.:......:.:.||......|.|....||... |::..|  ::| :.:.|.|.:
Mosquito   201 ATAFLKVHVKPFLIRGPHDQTVVEGTSVTFQCRVGGDPMPDVL-WRRSASGGNMPLNRVHILEDR 264

  Fly   686 EEFYSLLVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCE 750
            .     |..:|:.....|:|:|.|.||...::.|..|.|...|.....|:...:...:.:|..|:
Mosquito   265 S-----LRLEDVVLDDEGEYSCEADNAVGAISATGTLTVHSPPHLSIRPVPQVVEAPHDVSFECK 324

  Fly   751 AEGYPIPTITWFKGQGKGSKDFKPLSMRNHS----------LLLNLATDNDEG-YYMCQATNEIG 804
            :||.|.||..| ..:|..:..|...|:....          |.|...|.:|.| ..:|.|.|.:|
Mosquito   325 SEGRPKPTTFW-SIEGNRTLIFPGTSIDRFETTYTQESLTVLTLTQTTKSDNGLVIVCSAVNSVG 388

  Fly   805 AGLKKTIRINV-----NEPARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNGRIDLNNF 864
            : :....|:.|     ..|........|.:......|::.|:|.|:....|.|..:...: :.:.
Mosquito   389 S-VSVRARLMVASQDDRPPPIIILGPTNQTLPSKSTVSMACNAVGNPNPFISWYLDGNPV-VPSE 451

  Fly   865 RFSIAEMKT------EKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQIIFLAVQ--------- 914
            |.:|.|..|      |||.            |.|:|.|:|.:..|::....||.|:
Mosquito   452 RINITENGTLLLRELEKGT------------DQGLYTCVASSRSGKSTWSAFLRVESPTNPNVNF 504

  Fly   915 -------ERPDTPSHLEIFEVGSRTVKLSWRRPF-DGNSPVLSYLVQ------------------ 953
                   |.|..|...:|..:.:.::.:||.... .|.|.:..||::
Mosquito   505 YRAPEPSEFPSAPGKPQIVNISNSSITISWLPSIKSGASDINGYLIEVFSSDMAKGWTTVPFKVS 569

  Fly   954 -----YQALKYLQSHGSLAAAGGDWNGHVINVSLPSTSISRSYD--SDLRESAIVAGLTPATTFL 1011
                 |..:....|:..:..|..|....:.::.....||.|.::  .|:       .|:.|...|
Mosquito   570 STSYSYSPISPNVSYIFIVRAENDQGLGIPSLMSDPVSIGREFNHGEDI-------NLSEAQATL 627

  Fly  1012 IRMQAINEIERSAYTEAIVLKTQEEAPTEAPSNVQVQTGGESELIVTWQIPPRESWNGELI-GYT 1075
            ...|.:|.:|.:|              |:|.|           :.:.|:|.     ||:.: |:.
Mosquito   628 SSGQVVNLLEANA--------------TDATS-----------VRLAWEIV-----NGQYVEGFY 662

  Fly  1076 VNCSEEKQNINFISVVNSSLKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIFG 1140
            :...:...|..:.::       |::.|...:..|:.||.|::.|        .|...|:...|.|
Mosquito   663 IYSRKVNSNGTYRTL-------TVLHGGGASACTINGLEKFTEY--------EFFLVPFYKTIQG 712

  Fly  1141 --------TTAEGVPEAAPQNVNCTALSSQSLKISWLEPP--------LQFHGGIIQGYKILYRP 1189
                    .|.|.||.|:|.|:....|::.::.:.| |||        |:.:..||:||.
Mosquito   713 RPSNSRSTCTLEDVPTASPVNLEAVLLNTSAVYLKW-EPPSNSTINGKLKHYHIIIRGYD----- 771

  Fly  1190 IVHQIDFPAKLEIKRTSNLET---YLHTLHKASNYSIRVLAYTATGDGLASHPLFCQTD 1245
             ||.|   :|:....|.:.|.   .|..|.....||:.:.|.|..|.|..|.|...:.|
Mosquito   772 -VHNI---SKVLTNMTVDGEAPKLLLANLSAGVTYSVSIAASTKVGIGPYSIPSILRLD 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165	21/77 (27%)
		IGc2	553..619	CDD:197706	21/66 (32%)
		I-set	634..724	CDD:254352	22/92 (24%)
		ig	645..712	CDD:278476	17/69 (25%)
		IG_like	734..815	CDD:214653	22/91 (24%)
		Ig	745..815	CDD:299845	21/80 (26%)
		I-set	820..913	CDD:254352	22/98 (22%)
		Ig	838..920	CDD:299845	23/103 (22%)
		FN3	917..1033	CDD:238020	24/141 (17%)
		FN3	1040..1142	CDD:238020	19/110 (17%)
		fn3	1150..1237	CDD:278470	26/97 (27%)
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
AgaP_AGAP010242	XP_554155.3	Ig	18..113	CDD:299845	27/98 (28%)
		I-set	19..112	CDD:254352	27/97 (28%)
		I-set	118..207	CDD:254352	25/96 (26%)
		Ig	121..207	CDD:299845	25/93 (27%)
		I-set	211..298	CDD:254352	22/92 (24%)
		Ig	228..298	CDD:299845	19/75 (25%)
		I-set	302..398	CDD:254352	23/97 (24%)
		Ig	319..406	CDD:299845	22/88 (25%)
		I-set	407..494	CDD:254352	22/99 (22%)
		IGc2	422..484	CDD:197706	18/74 (24%)
		FN3	514..600	CDD:238020	13/85 (15%)
		FN3	636..722	CDD:238020	22/130 (17%)
		FN3	731..824	CDD:238020	28/102 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910