DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and AgaP_AGAP010185

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_554085.3	Gene:	AgaP_AGAP010185 / 3292140	VectorBaseID:	AGAP010185	Length:	153	Species:	Anopheles gambiae

Alignment Length:	175	Identity:	39/175 - (22%)
Similarity:	62/175 - (35%)	Gaps:	53/175 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 LVIKNVEPGRDQGIYTCIVR-SRAGEEARRD-MQLNVNSPPVIEPFKFPKNLQ--EGGRAQITCA 656
            |.|.|....||.|.:.|.|: |..|.:..:: ..|.|.:||. .||..|..|:  |..:..:||:
Mosquito    12 LTIMNTSYSRDNGRFECRVKASGTGADVHQEYYNLTVLTPPQ-PPFVEPVELRATEDEKFDLTCS 75

  Fly   657 VSSGDMPIYFSWKKDDSSIP----------------SSLQITEKKEEFYSLLVFKDISARHSGKY 705
            ...|......:|.:..|..|                |:|.|..::|:             ...|:
Mosquito    76 SIGGSPDPTITWYRVGSEKPLKSTITKGGSKDLRTSSTLSIVPRRED-------------DGAKF 127

  Fly   706 TCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCE 750
            .|...|.|..               ..:.::|.:    |:|:|||
Mosquito   128 RCVVWNRAMS---------------EKDKLETTV----TLSVNCE 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165
		IGc2	553..619	CDD:197706	9/23 (39%)
		I-set	634..724	CDD:254352	20/107 (19%)
		ig	645..712	CDD:278476	14/84 (17%)
		IG_like	734..815	CDD:214653	6/17 (35%)
		Ig	745..815	CDD:299845	4/6 (67%)
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
AgaP_AGAP010185	XP_554085.3	Ig	55..131	CDD:299845	17/88 (19%)
AgaP_AGAP010185	XP_554085.3	IG_like	59..150	CDD:214653	19/122 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910