DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and dpr8

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	55/217 - (25%)
Similarity:	92/217 - (42%)	Gaps:	31/217 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 SNAAAKVNYTAELQVRVAPRWRYEPMDTAI------MLGNTISINCEAEGYPIPTITWFK----- 763
            ::.|:|..:|..||....|.......||.|      ::|.|:.:.|..:.....|::|.:
  Fly    19 TDGASKRFFTDFLQDLPTPGTGGPTFDTTIGTNITGLVGKTVKLTCRVKNLGNRTVSWVRHRDIH 83

  Fly   764 ----GQGKGSKDFKPLSMRN-H----SLLLNLATDNDEGYYMCQ--ATNEIGAGLKKTIRINVNE 817
                |:...:.|.:..:|.: |    :|.:..|...|.|.|.||  .|..||    .::.:|:.|
  Fly    84 LLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYAQRKDSGIYECQISTTPPIG----HSVYLNIVE 144

  Fly   818 PARFEQSARNISSRRNDPVTLDCHAK--GDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGV--D 878
            |.........:...|...:.|.|..|  .:.|.|:.|:.|...|:.::.|..|: :.|||||  .
  Fly   145 PVTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSHNREIINFDSPRGGIS-LVTEKGVLTT 208

  Fly   879 SQLTIGHSDRHDSGVYRCIAEN 900
            |:|.:..:...|||:|.|...|
  Fly   209 SRLLVQKAITQDSGLYTCTPSN 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352	4/13 (31%)
		ig	645..712	CDD:278476	0/1 (0%)
		IG_like	734..815	CDD:214653	22/102 (22%)
		Ig	745..815	CDD:299845	17/85 (20%)
		I-set	820..913	CDD:254352	24/85 (28%)
		Ig	838..920	CDD:299845	23/67 (34%)
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	16/79 (20%)
		V-set	52..143	CDD:284989	20/94 (21%)
		IG_like	153..238	CDD:214653	24/79 (30%)
		ig	153..232	CDD:278476	24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810