DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and Negr1

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:252 Identity:59/252 - (23%)
Similarity:94/252 - (37%) Gaps:62/252 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   305 LLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSAI 369
            |.|:|.|..|.|.:.|....|...:.:::.|:|.....::.:.....:|.|......|..||...
Mouse    97 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV
QVPPKIYDISNDMTINEGTNVTLTCLATGKPE 161

  Fly   370 DAIDWLH---NGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQRA------- 424
            ..|.|.|   :.||.          :|.::|.     :..:.|...|.|:|..||..:       
Mouse   162 PVISWRHISPSAKPF----------ENGQYLD-----IYGITRDQAGEYECSAENDVSFPDVKKV 211

  Fly   425 -----SAQAMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSL 484
                 .|..:.|:|.|             .|.||....::|..:|.|||.|.|....:.:.:   
Mouse   212 RVIVNFAPTIQEIKSG-------------TVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFN--- 260

  Fly   485 HHRFAIGQFVDMSGDVI------SHLNISHVRPDDGGLYKCVASNSMGSVQHSARLN 535
                  ||    .|.:|      |.|.:::|..:..|.|.|||:|.:|:...|..||
Mouse   261 ------GQ----QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352 9/31 (29%)
Ig 264..334 CDD:143165 8/28 (29%)
I-set 345..433 CDD:254352 20/102 (20%)
Ig 358..431 CDD:143165 17/87 (20%)
Ig 456..533 CDD:143165 22/82 (27%)
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
Negr1XP_036019026.1 FR1 38..55 CDD:409353
Ig strand A' 40..46 CDD:409353
IG_like 41..129 CDD:214653 9/31 (29%)
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353 7/17 (41%)
Ig strand D 84..91 CDD:409353
Ig strand E 94..100 CDD:409353 1/2 (50%)
Ig strand F 107..115 CDD:409353 2/7 (29%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 17/72 (24%)
Ig strand B 150..157 CDD:409353 1/6 (17%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 1/10 (10%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 25/101 (25%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 1/3 (33%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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