DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and Cd300lf

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_017452644.1	Gene:	Cd300lf / 287818	RGDID:	1309733	Length:	351	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	60/322 - (18%)
Similarity:	95/322 - (29%)	Gaps:	126/322 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   750 EAEGYPIPTIT---------------WFKGQGKGSKDFK-------PLSMRNHSLLLNLATD--- 789
            |..||...::|               |.:|..:.|.:.:       .|...||..:.:..|:
  Rat    28 EVSGYEQGSLTVWCRYGSWWKDYSKYWCRGPKRSSCEIRVETDASERLVKENHVSIRDDQTNFTF 92

  Fly   790 ---------NDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPVTLDCHAKGD 845
                     :|.|.|.|..|.   ||.....:::|           :|:.....|.|:.......
  Rat    93 TVTMEDLRMSDAGIYWCGITK---AGYDHMFKVHV-----------SINPATQSPTTVPTTPTTT 143

  Fly   846 EPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSD-RHDSG----------------- 892
            ...||               |::.....|....|..|..:|| |:|||
  Rat   144 STTTI---------------FTVTTTVKETSTLSTQTSHYSDNRYDSGGVGDGNGFLDLSVLLPV 193

  Fly   893 ---------------VYRCI------AENPYGRAEQIIFLAVQERPDTPSHLEIFEVGSRTVKLS 936
                           .:|.:      |..|.|:.:      |.:|||        |..||.:..|
  Rat   194 ISAALLLLLLVVSLIAWRMVRRQKKAAGPPSGQVK------VSQRPD--------EETSRLLSPS 244

  Fly   937 WRRPFDGNSPVLSYLVQYQALKY-------LQSHGSLAAAGGDWNGHVINVSL---PSTSIS 988
            :...|....|.|...:.|..|..       |:...|::::|.|....|..|::   |...||
  Rat   245 FPCFFTSLEPPLEDDLCYANLSLQQPRTSPLKKGSSMSSSGKDHQEEVEYVTMAPFPREEIS 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653	18/98 (18%)
		Ig	745..815	CDD:299845	18/98 (18%)
		I-set	820..913	CDD:254352	19/131 (15%)
		Ig	838..920	CDD:299845	20/120 (17%)
		FN3	917..1033	CDD:238020	20/82 (24%)
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
Cd300lf	XP_017452644.1	IG_like	26..126	CDD:214653	19/111 (17%)
		Ig_pIgR	28..124	CDD:143193	18/98 (18%)
		SIT	210..317	CDD:291975	26/111 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910