DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dscam3 and dpr9

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	NP_001287332.1	Gene:	dpr9 / 2768670	FlyBaseID:	FBgn0038282	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	331	Identity:	74/331 - (22%)
Similarity:	118/331 - (35%)	Gaps:	96/331 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ATQVPG-----LRKISGNGTLHFPPFLAQ-YYRT--DVHEATYRCRASNEAGTVLSRNVQVHAVV 136
            ||.:.|     |.|.|...:..|...||. ::|.  |:.||       ..||....:
  Fly   211 ATTITGIPSSSLHKASSASSNTFSSQLASGFHRNSIDLEEA-------RNAGPYFDK-------- 260

  Fly   137 RRQFHVHVENTEVYLGNSALIKCAIPEY-VRPYVRVASWHRGEEILLPDLSDVAGRYVVLAASGD 200
                 ...:|....||.:|.:.|.:... .:..:...||.|..:|.|.    ..|||...:....
  Fly   261 -----AFSKNVTALLGKTAYLNCRVKNLGNKTMLLQVSWVRHRDIHLL----TVGRYTYTSDQRF 316

  Fly   201 LYVRSVRSEDGLMK-----------FSCLVTNTLNGERQRSDAVMLQVKELSKNL--APRTTQKP 252
            ..:...::||.:::           :.|.|:.|    ...|..:.|.|.|.|..:  ||
  Fly   317 RAIHQPQTEDWMLQIKYPQHRDSGIYECQVSTT----PHMSHYIHLNVVEPSTEIIGAP------ 371

  Fly   253 VMEIHVERGNDVHLPCNIQGNPFP---IFTWYRVSDSAALYPIPSSQRVI--------------- 299
              ::::|.|:.::|.|.||.:|.|   || |...:      ..||..::|
  Fly   372 --DLYIESGSTINLTCIIQNSPEPPAYIF-WNHNN------AFPSHPQIINYDSPRGGVSVVTNK 427

  Fly   300 --LSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNC 362
              .:.:.||||:|...|:|.:.|..||           :....|:||:|..|....|.|..:.|.
  Fly   428 GDTTTSFLLIKSARPSDSGHYQCNPSN-----------AKPKSVTVHVLNGVSHSVSRGVPSSNA 481

  Fly   363 TTTGSA 368
            ....||
  Fly   482 ARGTSA 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652	15/60 (25%)
		Ig	56..125	CDD:143165	15/52 (29%)
		I-set	246..337	CDD:254352	25/110 (23%)
		Ig	264..334	CDD:143165	22/89 (25%)
		I-set	345..433	CDD:254352	7/24 (29%)
		Ig	358..431	CDD:143165	3/11 (27%)
		Ig	456..533	CDD:143165
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
dpr9	NP_001287332.1	Ig	263..361	CDD:299845	20/105 (19%)
		IG_like	263..360	CDD:214653	20/104 (19%)
		IG_like	371..464	CDD:214653	27/118 (23%)
		IGc2	377..456	CDD:197706	23/96 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810