DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dscam3 and Emb

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:NP_034460.3 Gene:Emb / 13723 MGIID:95321 Length:330 Species:Mus musculus


Alignment Length:367 Identity:73/367 - (19%)
Similarity:122/367 - (33%) Gaps:106/367 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 PCNIQGNPF-PIFTWYRVSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQR 330
            |...:|:|. |.||           .:|..:.::...:.|.:|:.:                   
Mouse    28 PDPAEGDPTDPTFT-----------SLPVREEMMAKYSNLSLKSCN------------------- 62

  Fly   331 IEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSA---IDAIDWLHNGKPLQANNALTTGRD 392
              |.::..|.|||.   :..|:.........|..|.:.   :..:.|..:.:||:......|.:.
Mouse    63 --ISVTEKSNVSVE---ENVILEKPSHVELKCVYTATKDLNLMNVTWKKDDEPLETTGDFNTTKM 122

  Fly   393 NIRFLSKSSLLVQNVGRRDRGVYQCLVENQRASAQAMAELKLGDT----VPEL------IYTFIE 447
            .....|:...:|.|  .:..|.|.|:          ..|.:|..|    ||:.      :..:: 
Mouse   123 GNTLTSQYRFIVFN--SKQLGKYSCV----------FGEKELRGTFNIHVPKAHGKKKSLIAYV- 174

  Fly   448 QNVRPGPLISLKCSASGSPPPQFAWLLDSQ----PIMDVSLHHRFAIGQFVDMSGDVISHLN--- 505
                 |....|||......|..:.|.:.::    || |...:.::.|..         ||.|   
Mouse   175 -----GDSTVLKCVCQDCLPLNWTWYMGNETAQVPI-DAHSNEKYIING---------SHANETR 224

  Fly   506 --ISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGPIKAVAGE-----DIIVHC--- 560
              |.|:..:|||.|.|.|:..:|..:....|.|..  ::..:.|..|:..|     .||:.|   
Mouse   225 LKIKHLLEEDGGSYWCRATFQLGESEEQNELVVLS--FLVPLKPFLAILAEVILLVAIILLCEVY 287

  Fly   561 -------PFAGYPVEQIRWEKAHQELTTSNH---YELASVAD 592
                   |.||...|||...|:.......|:   |.....||
Mouse   288 THKKKNDPDAGKEFEQIEQLKSDDSNGIENNVPRYRKTDSAD 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352 10/70 (14%)
Ig 264..334 CDD:143165 9/67 (13%)
I-set 345..433 CDD:254352 14/90 (16%)
Ig 358..431 CDD:143165 12/75 (16%)
Ig 456..533 CDD:143165 21/85 (25%)
IGc2 553..619 CDD:197706 15/58 (26%)
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
EmbNP_034460.3 Ig 85..146 CDD:143165 11/62 (18%)
IG_like 168..257 CDD:214653 23/104 (22%)
Ig 179..250 CDD:143165 21/80 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 293..330 11/37 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.