DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and AgaP_AGAP009183

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_319953.4	Gene:	AgaP_AGAP009183 / 1280143	VectorBaseID:	AGAP009183	Length:	317	Species:	Anopheles gambiae

Alignment Length:	232	Identity:	54/232 - (23%)
Similarity:	93/232 - (40%)	Gaps:	45/232 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 GQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGP--IKAVAG 553
            |.|..|..:..:|..|               ::.:||:   |.|    |..||.||.  :..:..
Mosquito    84 GNFSKMYFETDNHTTI---------------ASQVGSI---AVL----PCAVRNIGEGVVSWIRR 126

  Fly   554 EDI-IVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSR 617
            :|. ::...|..|..:: |:...|.|.|           :...|.||.|:. ||.|:|.|.|.:.
Mosquito   127 KDYHLLTIGFTTYSSDE-RFNIIHSEDT-----------EEWPLQIKYVQL-RDAGLYECQVSTH 178

  Fly   618 AGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITC-AVSSGDMPIYFSWKKDDSSI----PS 677
            ........:.:......:..|.:  |.|:.|...::|| .|.|.:.|:|..|..::..|    ..
Mosquito   179 PPTSIFVKLDVVEAKAEIFGPSE--KYLKPGSMLRLTCRVVQSNEPPLYIFWYHNNRMINYDAHR 241

  Fly   678 SLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA 714
            .:.::.:.:..||.||....:..:||.|:|.::||.|
Mosquito   242 GVNVSTEADNRYSELVISHTNTLNSGNYSCVSNNAVA 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165	7/41 (17%)
		IGc2	553..619	CDD:197706	17/66 (26%)
		I-set	634..724	CDD:254352	23/86 (27%)
		ig	645..712	CDD:278476	18/71 (25%)
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
AgaP_AGAP009183	XP_319953.4	IG_like	102..189	CDD:214653	26/106 (25%)
		Ig	104..189	CDD:299845	26/104 (25%)
		IG_like	199..276	CDD:214653	20/78 (26%)
		Ig	210..275	CDD:143165	16/64 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810