DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and AgaP_AGAP002707

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:XP_312221.5 Gene:AgaP_AGAP002707 / 1273261 VectorBaseID:AGAP002707 Length:499 Species:Anopheles gambiae


Alignment Length:481 Identity:92/481 - (19%)
Similarity:155/481 - (32%) Gaps:149/481 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   479 IMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPD------DGGLYKCVASNSMGSVQHSARLNVY 537
            :.|.|.|   ::.:.|.|.|.....:..:|..|.      .|.|...|:|:|..:.......|.|
Mosquito    96 VTDASTH---SLPEAVAMHGADPGPMVTTHTAPSSARASPSGTLLGGVSSDSASTAAQYGGSNAY 157

  Fly   538 G------PPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHY-----ELASVA 591
            .      |..:..:..::    ...|||    ..|.:    .|.|.|    .|:     |..:|.
Mosquito   158 NKYTTFRPLLIPTLPDVR----RSRIVH----SMPYQ----SKHHHE----RHWGPFFEEPVNVT 206

  Fly   592 DGGQL---------VIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNS--PPVIEPFKFPKNL 645
            .|..|         .|.|...|..:......:|....:.:...:..|..|  |.:...|::|.| 
Mosquito   207 SGAALQVGYHLSTEAILNCRVGMLKDKTVMWIRRTTDKVSLLTVGNNTYSGDPRIKVKFQYPNN- 270

  Fly   646 QEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHSGKYTCYAS 710
                                  |:                      |....|.:..:|.|.|..|
Mosquito   271 ----------------------WR----------------------LHINPIKSDDAGLYMCQVS 291

  Fly   711 NAAAKV---NYTA-ELQVRVAPRWRYEPMDTAIMLGNTISINCE-AEGY--PIPTITWFKGQGKG 768
            ....:|   |.|. |..||:.....||..|....||:||.|:|: :..|  .:|......||.:.
Mosquito   292 THPPRVFATNLTVLEPAVRIVDEMGYEFSDRYYKLGSTIEISCQVSTSYLATLPPSPKSAGQQQR 356

  Fly   769 SKDFKPLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRN 833
            ||                             |:.:||....     ::|.|:....|....::.:
Mosquito   357 SK-----------------------------TSPVGASANA-----LDETAKTGSKATKDDNKLS 387

  Fly   834 DPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIA 898
            |         ..|...|.||::...:. .:.:.|.:  .|::.:.|:|:|..::|..:|||.|..
Mosquito   388 D---------STERGLISWTKDGAELP-KDVKMSFS--GTKQWLISRLSILQANRVHNGVYNCTV 440

  Fly   899 ENPYGRAEQIIFLAVQERPDTPSHLE 924
            .....:|.|:..|    ..:||:.::
Mosquito   441 AGKQSQAAQVQVL----NGETPAAVQ 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352
Ig 264..334 CDD:143165
I-set 345..433 CDD:254352
Ig 358..431 CDD:143165
Ig 456..533 CDD:143165 13/59 (22%)
IGc2 553..619 CDD:197706 16/79 (20%)
I-set 634..724 CDD:254352 14/93 (15%)
ig 645..712 CDD:278476 7/66 (11%)
IG_like 734..815 CDD:214653 16/83 (19%)
Ig 745..815 CDD:299845 12/72 (17%)
I-set 820..913 CDD:254352 19/92 (21%)
Ig 838..920 CDD:299845 17/81 (21%)
FN3 917..1033 CDD:238020 2/8 (25%)
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
AgaP_AGAP002707XP_312221.5 IG_like 221..304 CDD:214653 19/127 (15%)
Ig <237..305 CDD:299845 17/112 (15%)
Ig <395..443 CDD:299845 13/50 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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