DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and AgaP_AGAP011128

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_309518.4	Gene:	AgaP_AGAP011128 / 1270797	VectorBaseID:	AGAP011128	Length:	269	Species:	Anopheles gambiae

Alignment Length:	194	Identity:	54/194 - (27%)
Similarity:	78/194 - (40%)	Gaps:	36/194 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNI----RFLS---KSS----LLVQNVG 408
            |..|...|........::.|:.    ::.::.||..|...    ||.|   :||    |.::.|.
Mosquito    37 GTHAYLPCKVKQLGNKSVSWVR----VRDDHILTVDRMTFIADERFQSFYVESSGVWTLQIKYVQ 97

  Fly   409 RRDRGVYQCLVENQRASAQAMAELKLGDTVP--ELIYTFIEQNVRPGPLISLKCSASGS--PPPQ 469
            .||.|:|:|.|..:   .:..|.:.|...||  |||.. .::.|:.|..:.|:|...|:  ||..
Mosquito    98 ARDAGIYECQVSTE---PKISARVHLHVVVPRTELIGD-SDRYVKAGSAVILRCVVRGALEPPSY 158

  Fly   470 FAWLLDSQPIMDVSLH------HRFAIGQFVDMSGDV---ISHLNISHVRPDDGGLYKCVASNS 524
            ..|...:|.|...|..      .|.|    .|:.||:   |..|.|...|..|.|.|.|..|||
Mosquito   159 IIWYHGTQQIFTESRRGWKTQLDRGA----PDLDGDIHSTIGSLIIESTRKKDSGNYSCSPSNS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352	21/88 (24%)
		Ig	358..431	CDD:143165	19/83 (23%)
		Ig	456..533	CDD:143165	25/80 (31%)
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
AgaP_AGAP011128	XP_309518.4	IG_like	30..122	CDD:214653	22/91 (24%)
		Ig	32..123	CDD:299845	22/92 (24%)
		IG_like	133..227	CDD:214653	27/90 (30%)
		IGc2	140..218	CDD:197706	24/81 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810