DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam3 and Cd80

DIOPT Version :9

Sequence 1:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster
Sequence 2:XP_036015651.1 Gene:Cd80 / 12519 MGIID:101775 Length:314 Species:Mus musculus


Alignment Length:238 Identity:54/238 - (22%)
Similarity:84/238 - (35%) Gaps:69/238 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   266 LPCNIQGNPFPIFTWYRVSDSAAL-YPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQ 329
            :.||.|          .:.|:..| :|.|   |:||...||:           .:.|.|:...||
Mouse     9 MACNCQ----------LMQDTPLLKFPCP---RLILLFVLLI-----------RLSQVSSDVDEQ 49

  Fly   330 RIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSAIDAIDWLHNGK-------------PL 381
               :..||...|   :||          ..:|......:.|.|.|..:.|             |.
Mouse    50 ---LSKSVKDKV---LLP----------CRYNSPHEDESEDRIYWQKHDKVVLSVIAGKLKVWPE 98

  Fly   382 QANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQRASAQAMAELKLGDTVPELIYTFI 446
            ..|..|   .||..:    ||::..:...|||.|.|:|:.:......:..|.|  ....:...|.
Mouse    99 YKNRTL---YDNTTY----SLIILGLVLSDRGTYSCVVQKKERGTYEVKHLAL--VKLSIKADFS 154

  Fly   447 EQNVRP--GPLISLK---CSASGS-PPPQFAWLLDSQPIMDVS 483
            ..|:..  .|....|   |.|||. |.|:|:||.:.:.:..::
Mouse   155 TPNITESGNPSADTKRITCFASGGFPKPRFSWLENGRELPGIN 197

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352 16/71 (23%)
Ig 264..334 CDD:143165 16/68 (24%)
I-set 345..433 CDD:254352 20/100 (20%)
Ig 358..431 CDD:143165 18/85 (21%)
Ig 456..533 CDD:143165 10/32 (31%)
IGc2 553..619 CDD:197706
I-set 634..724 CDD:254352
ig 645..712 CDD:278476
IG_like 734..815 CDD:214653
Ig 745..815 CDD:299845
I-set 820..913 CDD:254352
Ig 838..920 CDD:299845
FN3 917..1033 CDD:238020
FN3 1040..1142 CDD:238020
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
Cd80XP_036015651.1 IgV_CD80 47..150 CDD:319335 27/127 (21%)
Ig strand B 58..62 CDD:319335 3/16 (19%)
Ig strand C 75..79 CDD:319335 1/3 (33%)
Ig strand E 110..114 CDD:319335 2/7 (29%)
Ig strand F 124..129 CDD:319335 2/4 (50%)
Ig strand G 142..145 CDD:319335 2/4 (50%)
IgC1_CD80 153..243 CDD:409505 13/45 (29%)
Ig strand B 169..173 CDD:409505 1/3 (33%)
Ig strand C 183..187 CDD:409505 1/3 (33%)
Ig strand E 213..217 CDD:409505
Ig strand F 224..229 CDD:409505
Ig strand G 237..240 CDD:409505
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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