DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and mpzl1

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_004912325.1	Gene:	mpzl1 / 100490085	XenbaseID:	XB-GENE-953820	Length:	272	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	52/256 - (20%)
Similarity:	75/256 - (29%)	Gaps:	112/256 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 GERQRSDAVMLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQ-----GNPFPIFTWYRVS 284
            |||.|...:.||:.....:.:......|..::.:|.|....||||.:     |....: ||....
Frog    11 GERWRRGLLALQLLLCYVHFSTSADVSPAEDLFIENGTQALLPCNFKSLETTGTEQSV-TWTFRP 74

  Fly   285 DSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQV 349
            ||.:.:.           |:.:..|.                           |||
Frog    75 DSGSNFV-----------TIFVYSNG---------------------------NSY--------- 92

  Fly   350 QIVNSGGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGV 414
                .|....|.        |.|.|...          .|.:|       :|:.|.|:..||.|.
Frog    93 ----PGNAGQFK--------DRISWAGE----------LTRKD-------ASIKVDNMQFRDNGT 128

  Fly   415 YQCLVENQRASAQAMAELKLGDTVPEL--IYTFI--------EQNVRP---GP-LISLKCS 461
            |.|:|.|                :|:|  :|..|        ||...|   || ||.:.|:
Frog   129 YTCIVVN----------------LPDLGSLYKQIQLRVVEKGEQKNLPLSNGPLLIGIICA 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352	14/95 (15%)
		Ig	264..334	CDD:143165	11/74 (15%)
		I-set	345..433	CDD:254352	17/87 (20%)
		Ig	358..431	CDD:143165	16/72 (22%)
		Ig	456..533	CDD:143165	2/6 (33%)
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
mpzl1	XP_004912325.1	Ig	35..150	CDD:386229	38/207 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910