DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam3 and si:ch211-9d9.7

DIOPT Version :9

Sequence 1:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster
Sequence 2:	XP_021322083.1	Gene:	si:ch211-9d9.7 / 100150985	ZFINID:	ZDB-GENE-060503-422	Length:	288	Species:	Danio rerio

Alignment Length:	270	Identity:	53/270 - (19%)
Similarity:	95/270 - (35%)	Gaps:	54/270 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   490 IGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVY----------------- 537
            |.:|:...|.....:.::.:...|...:.|    |.|.:|...:|.|.
Zfish    11 IPEFISDDGKSSFTVLMTELTLSDSEWFFC----SAGDLQVPVQLTVTKVIFVCCFCLGVESFEG 71

  Fly   538 GPPYVRAIGPIKAVAGEDIIVHCPF-AGYPVEQIRW-----EKAHQELTTSNHYELASVADGG-- 594
            |..:...:.|     |..:.:.|.: ...|.::..|     |......||..:..:....|..
Zfish    72 GSNHTITVKP-----GGSVTIPCYYDEKNPPQKKYWYSVIGESRKYTNTTEENLSVIDHPDQSLF 131

  Fly   595 QLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSS 659
            .:.::|::..:..|.|.|.|.:........::.|.|:|.|.:.......:..||....:.|..||
Zfish   132 TVTMRNLQENKHNGKYYCTVETGQKSNVTYELFLQVHSAPDVSVMNSSVSGHEGDDVSVQCFYSS 196

  Fly   660 GDMPIY---------------FSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHSGKYTCYA 709
            |    |               ||.||.|:|..||:||::..|..:::|: ..:....||.:.|..
Zfish   197 G----YKDKQKRWCRYKDQKCFSQKKTDTSQSSSVQISDDGESSFTVLM-TGLRLSDSGWFFCSV 256

  Fly   710 SNAAAKVNYT 719
            .:....|..|
Zfish   257 GHQTIPVKLT 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352
		Ig	358..431	CDD:143165
		Ig	456..533	CDD:143165	8/42 (19%)
		IGc2	553..619	CDD:197706	13/73 (18%)
		I-set	634..724	CDD:254352	25/101 (25%)
		ig	645..712	CDD:278476	22/81 (27%)
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
si:ch211-9d9.7	XP_021322083.1	Ig	76..168	CDD:325142	15/96 (16%)
si:ch211-9d9.7	XP_021322083.1	Ig	180..266	CDD:325142	23/90 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910