DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cysu and NOX3

DIOPT Version :9

Sequence 1:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_056533.1	Gene:	NOX3 / 50508	HGNCID:	7890	Length:	568	Species:	Homo sapiens

Alignment Length:	323	Identity:	63/323 - (19%)
Similarity:	97/323 - (30%)	Gaps:	127/323 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GEQLQTAHGS------DCALLLAGPGRSSVYDYNVNLFRGT----LNPYNNGPGTCITYDAINAA 76
            |..|..|..|      :|.|:|....|:.     ::..|||    ..|:.......:.:..:.|.
Human    48 GSTLAWARASALCLNFNCMLILIPVSRNL-----ISFIRGTSICCRGPWRRQLDKNLRFHKLVAY 107

  Fly    77 YLDARKRIHVAQ-----PKSDWKPEELATVGELLLDISIQLARTYGLSYEEIEKGLPTIDTSKTL 136
            .:.....||:..     .:..|...|.|   :.||....:|..|...||....:..|| :|:..|
Human   108 GIAVNATIHIVAHFFNLERYHWSQSEEA---QGLLAALSKLGNTPNESYLNPVRTFPT-NTTTEL 168

  Fly   137 IREVCPPFFAGVE------------------CRPGKYRRF------------------------- 158
            :|.:     |||.                  .|...|..|
Human   169 LRTI-----AGVTGLVISLALVLIMTSSTEFIRQASYELFWYTHHVFIVFFLSLAIHGTGRIVRG 228

  Fly   159 ---DGL-CNNI-----EHPTW------------GAANAPFQRLIGP--LYSDGINAPRISVTGR- 199
               |.| .:||     .:..|            |...:.::.::||  ||:    ..||....|
Human   229 QTQDSLSLHNITFCRDRYAEWQTVAQCPVPQFSGKEPSAWKWILGPVVLYA----CERIIRFWRF 289

  Fly   200 --DLPFSRVVSRTMHPDD---------GFHDHAGTVMVI--------AWGQFMDHDFTLTGTP 243
              ::..::|||   ||..         ||....|..:::        .|     |.||||..|
Human   290 QQEVVITKVVS---HPSGVLELHMKKRGFKMAPGQYILVQCPAISSLEW-----HPFTLTSAP 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	30/157 (19%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655
NOX3	NP_056533.1	Ferric_reduct	60..217	CDD:280043	31/170 (18%)
NOX3	NP_056533.1	NOX_Duox_like_FAD_NADP	295..568	CDD:99783	15/58 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910