Protein Alignment cysu and Nox4

DIOPT Version :10

• Sequence 1: NP_650627.1
• Gene: cysu / 42100
• FlyBaseID: FBgn0038511
• Length: 753
• Species: Drosophila melanogaster
• Sequence 2: XP_006508075.1
• Gene: Nox4 / 50490
• MGIID: 1354184
• Length: 617
• Species: Mus musculus
• Alignment Length: 736
• Identity: 127/736 - (17%)
• Similarity: 203/736 - (27%)
• Gaps: 320/736 - (43%)

  Fly    49 NVNLFRGTLNPYNNGP-----------GTCITYDAINAAYLDARKRIHVAQPKSDWKPEELATVG 102
            ||.||..|...||.||           |.|::..:.:...|:.
Mouse    26 NVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNC---------------------- 68

  Fly   103 ELLLDISIQLARTYGLSYEEIEKGLPT------IDTSKTLIREVCPPFFAGVECRPGKYRRFDGL 161
            .|:|   :.:.||. |:|....:.:|:      :|.||||
Mouse    69 SLIL---LPMCRTV-LAYLRGSQKVPSRRTRRLLDKSKTL------------------------- 104

  Fly   162 CNNIEHPTWGAANAPFQ------RLIGPL-----YSDG---INAPRI-SVTGRDLPFSRVVSRTM 211
                 |.|.|.....|.      .|:..|     ||:.   :||.|. :...|.|.|:.:...|
Mouse   105 -----HITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFLELNAARYQNEDPRKLLFTTIPGLT- 163

  Fly   212 HPDDGFHDHAGTVMVIAWGQFMDHDFTLTGTPLDPINRNDPEECCKRPLHLKHPYCNEIRIPDDD 276
                      |..||:.  .|:    .:|.:..                        .||:.:.|
Mouse   164 ----------GVCMVVV--LFL----MVTASTY------------------------AIRVSNYD 188

  Fly   277 YFYRLFNV--------------KCIDFVRGFPSPRPGCKLGSRQQFNTLTGVIDANTVYGVKESF 327
            .|:...|:              ..:.:.....:..||| :...|..:....:.|.     |.|.|
Mouse   189 IFWYTHNLFFVFYMLLLLHVSGGLLKYQTNVDTHPPGC-ISLNQTSSQNMSIPDY-----VSEHF 247

  Fly   328 ARKLRTGYGGL-----------MRMNPVFQEYGLKDLL----PLKLDIPDE--GCTRPNKSMYCF 375
            ...|..|:..|           ....|.||.:..:..:    ||.|...:.  .|.|.||.:...
Mouse   248 HGSLPRGFSKLEDRYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSNKPVTII 312

  Fly   376 ----------------EGGEIRVNEQLVLTCMHTLMAREHNRLATALAQINKHW----------- 413
                            |..:.|..:.::|.|........|....|.|.|  |.|
Mouse   313 SVINHPSDVMELRMIKENFKARPGQYIILHCPSVSALENHPFTLTMLCQ--KRWQPWHSRVWIYS 375

  Fly   414 ----DDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQKDGYW-----------DG 463
                .|....::..::|.|.           :|...|....||:..:..|.|           ..
Mouse   376 FFVCSDAACHEDTSKMNHAF-----------LLCPTETKATFGVHFKVVGDWTERFRDLLLPPSS 429

  Fly   464 YDSTVNPGI---------IDSFAGAAFR-------------------FGHSLLPTAVERWSKAHK 500
            .||.:.|.|         ||...|:.|.                   |. |:|.|.::.|
Mouse   430 QDSEILPFIHSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFA-SILNTLLDDW----- 488

  Fly   501 FIASKRLSDLIRRPYDLYRAGVLDEYFMGLMNQVAQ---------AMDDSITQE-------VTNH 549
                        :||.|.|.     ||:.:...:..         .:.:...||       :..:
Mouse   489 ------------KPYKLRRL-----YFIWVCRDIQSFQWFADLLCVLHNKFWQENRPDFVNIQLY 536

  Fly   550 LFKKEGAR--FGMDLVSFNMQ-------------------RGREFGIPGYMEFRKFCGLPTSNTW 593
            |.:.:|.:  .|....:.|.:                   ||:..|:        ||..|:|.:
Mouse   537 LSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGV--------FCCGPSSIS- 592

  Fly   594 DEMYGSMPNETVLRYGSIFEH 614
             :...|:.|.. ..||:.||:
Mouse   593 -KTLHSLSNRN-NSYGTKFEY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..699	CDD:460804	103/613 (17%)
Nox4	XP_006508075.1	Ferric_reduct	69..205	CDD:426438	37/210 (18%)
		NOX_Duox_like_FAD_NADP	311..616	CDD:99783	57/348 (16%)